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TranscriptomicsZinc sensing by metal-responsive transcription factor 1 (MTF1) controls metallothionein and ZnT1 expression to buffer the sensitivity of the transcriptome response to zinc
Only a small number of genes are known direct targets of the zinc-responsive transcription factor MTF1; therefore, the aim of this study was to gain a more complete understanding of the MTF-1 regulated zinc-responsive component of the transcriptome. A targeted siRNA was used to deplete MTF1 express...
ORGANISM(S): Homo sapiens 
2016-02-24 | E-GEOD-76510 | biostudies-arrayexpress
TranscriptomicsExpression data from MTF mutant roots
Mutation of MTF in Arabidopsis increases Agrobacterium-mediated transformation susceptibility. Being a putative transcription factor, different genes controlling transformation may be regulated by MTF. We used microarrays to detail the global programme of gene expression and to identify genes that p...
ORGANISM(S): Arabidopsis thaliana 
2013-11-14 | E-GEOD-51236 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of liver-specific transcription in Mtf1 conditional knockout mice and control littermates to identify MTF-1 target genes and cadmium-inducible genes in the adult liver
A search for MTF-1 target genes and cadmium-inducible genes in the adult liver was performed by comparing liver-specific transcription in Mtf1 conditional knockout mice and control littermates.
ORGANISM(S): Mus musculus 
2005-10-01 | E-MEXP-438 | biostudies-arrayexpress
GenomicsCopper and MTF1: New roles for a classic metal sensing transcription factor in myogenesis
Copper and MTF1: New roles for a classic metal sensing transcription factor in myogenesis
PRJNA478204 | ENA
UnknownA novel function of the mitochondrial transcription factor Mtf1 in fission yeast; Mtf1 regulates the nuclear transcription of srk1.
Not available
S-EPMC3074130 | biostudies-literature
GenomicsTranscriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9
PRJNA550994 | ENA
GenomicsCopper and MTF1: New roles for a classic metal sensing transcription factor in myogenesis
MTF1 is a highly conserved metal-binding transcription factor in eukaryotes. MTF1 binds to DNA sequence motifs, termed metal response elements (MREs) to induce the expression of genes involved in metal and oxidative stress homeostasis. MTF1 is responsive to both metal excess and deprivation, and can...
ORGANISM(S): Mus musculus 
2019-10-04 | GSE116331 | GEO
GenomicsNext Generation Sequencing Facilitates Quantitative Analysis of Wild Type HCT116 and MTF1-KO HCT116 injected tumor Transcriptomes
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type HCT116 and MTF1-KO HCT116 injected tumor Transcriptomes
PRJNA787124 | ENA
UnknownA New Toolbox to Label Zinc-MTF1 Responsive Neuronal Populations Unravels Cellular Congruence between MTF1 Responses and T-type Calcium Channelopathies in an Experimental Model of Epilepsy.
Not available
S-EPMC12701871 | biostudies-literature
UnknownPrognostic and Immunological Role of Cuproptosis-Related Gene MTF1 in Pan-Cancer.
Not available
S-EPMC11414622 | biostudies-literature
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