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MetabolomicsMethionine Intervention Induces PD-L1 Expression to Enhance the Immune Checkpoint Therapy Response in MTAP-deleted Osteosarcoma
Osteosarcoma (OS), a malignant bone tumor with limited treatment options, exhibits low sensitivity to immune checkpoint therapy (ICT). Through genomics and transcriptomics analyses, we have identified a subgroup of OS with methylthioadenosine phosphorylase (MTAP) deletion, which contributes to ICT r...
2026-06-09 | MTBLS11985 | MetaboLights
UnknownAberrant CD200/CD200R1 expression and function in systemic lupus erythematosus contributes to abnormal T-cell responsiveness and dendritic cell activity.
Not available
S-EPMC3446504 | biostudies-literature
Proteomicssystematic proteomic of 20 cases of primary ESCC tumor tissue (T), matched normal tissue (N) and lymph node metastatic tissue (LN)
To obtain the global landscape of Khib in ESCC metastasis, 20 cases of primary ESCC tumor tissue (T), matched normal tissue (N) and lymph node metastatic tissue (LN) were subjected to systematic proteomic.
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD037295 | Pride
Proteomics Cancer metastasis 
ProteomicsQuantitative Khib proteomic analyses of 20 cases of primary ESCC tumor tissue (T), matched normal tissue (N) and lymph node metastatic tissue (LN)
To obtain the global landscape of Khib in ESCC metastasis, 20 cases of primary ESCC tumor tissue (T), matched normal tissue (N) and lymph node metastatic tissue (LN) were subjected to quantitative Khib proteomic analyses.
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD038252 | Pride
Proteomics Lysine 2-hydroxyisobutyrylation Cancer metastasis 
UnknownThe Role of Helper T Cells in Psoriasis.
Not available
S-EPMC8714744 | biostudies-literature
UnknownExtracellular Vesicles Expressing CD19 Antigen Improve Expansion and Efficacy of CD19-Targeted CAR-T Cells.
Not available
S-EPMC9830716 | biostudies-literature
ProteomicsSpatiotemporal Deciphering of Dynamic Proteome during Liquid-Liquid Phase Separation in Living Cells
We introduce the Composition of LLPS proteome Assembly by Proximity labeling assisted Mass spectrometry (CLAPM) to address such unmet need in this filed. We demonstrate CLAPM for instantaneously labeling and monitoring in situ proteome shifts within intracellular droplets that undergo spatiotemporal...
ORGANISM(S): Homo sapiens (Human) 
2025-03-26 | PXD051405 | Pride
Liquid-liquid phase separations  proximity labeling  proteomics  mass spectrometry  living cells  
UnknownGpr174-deficient regulatory T cells decrease cytokine storm in septic mice.
Not available
S-EPMC6408576 | biostudies-literature
UnknownModulation of mTOR Activity by μ-Opioid Receptor is Dependent upon the Association of Receptor and FK506-Binding Protein 12.
Not available
S-EPMC4477277 | biostudies-literature
UnknownEtoposide activates CD8<sup>+</sup> T cell anti-tumor immunity in osteosarcoma through MHC I upregulation via tumor-secreted IL-33 mediated signaling.
Not available
S-EPMC12718598 | biostudies-literature
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