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TranscriptomicsGenetics of gene expression responses to temperature stress in a sea urchin gene network (HTS)
Stress responses play an important role in shaping species distributions and robustness to climate change. We investigated how stress responses alter the contribution of additive genetic variation to gene expression during development of the purple sea urchin, Strongylocentrotus purpuratus, under in...
ORGANISM(S): Strongylocentrotus purpuratus 
2012-11-30 | E-GEOD-38606 | biostudies-arrayexpress
TranscriptomicsGenetics of gene expression responses to temperature stress in a sea urchin gene network
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Strongylocentrotus purpuratus 
2012-11-30 | E-GEOD-29504 | biostudies-arrayexpress
TranscriptomicsGenetics of gene expression responses to temperature stress in a sea urchin gene network (DASL)
Stress responses play an important role in shaping species distributions and robustness to climate change. We investigated how stress responses alter the contribution of additive genetic variation to gene expression during development of the purple sea urchin, Strongylocentrotus purpuratus, under in...
ORGANISM(S): Strongylocentrotus purpuratus 
2012-11-30 | E-GEOD-38644 | biostudies-arrayexpress
TranscriptomicsUndifferentiated Pleomorphic Sarcoma Model
Analysis of undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma-like tumors from LSL-KrasG12D, p53Fl/Fl mouse model of soft tissue sarcoma. Murine soft tissue sarcomas (n = 17) were compared to normal muscle (n = 4). Tumors were isolated surgically from soft tissue sarcomas generate...
ORGANISM(S): Mus musculus 
2010-03-03 | E-GEOD-16779 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human early stage non-small cell lung carcinoma to refine prognosis for adjuvant therapy
Abstract from paper - Potti A, et al Experiment Overall Design: Retrospective analysis of approximately 200 samples obtained from Duke, ACOSOG and CALGB to develop a Lung metagene predictor that would then be used to assess risk of recurrence and thus identify high risk patients with stage Ia non-sm...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-3593 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human breast tumors to identify age-specific differences of oncogenic pathway deregulation
Breast cancer arising in young women has a poorer prognosis, is less likely to be hormone sensitive, and represents a particularly challenging clinical entity. The biology driving the aggressive nature of breast cancer arising in young women has yet to be defined. Among 784 patients with early stag...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7849 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of breast cancer samples to predict response to anthracycline/taxane chemotherapy .
EORTC 10994 phase III breast cancer clinical trial comparing FEC (5-fluorouracil, cyclophosphamide, epirubicin) with ET (epirubicin, docetaxel). 161 needle biopsies of locally advanced or large operable breast tumours were hybridised to Affymetrix X3P chips. The array data from the ER negative ...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6861 | biostudies-arrayexpress
TranscriptomicsA 50-Gene Predictor of Recurrence as a Guide to Therapy in Early-Stage Colon Cancer.
Gene expression profiles reflect unique aspects of individual biologic phenotypes and may characterize the heterogeneity of solid tumors. Using previously-described methodologies that employ DNA microarray data, a 50-gene expression profile (metagene) that predicts risk of recurrence in early stage ...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-10402 | biostudies-arrayexpress
UnknownBaricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis.
Not available
S-EPMC9333998 | biostudies-literature
UnknownCasirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC8830904 | biostudies-literature
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