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Regulation of metablism by mitochondrial MUL1 E3 ubiquitin ligase
Inactivation of mitochondrial MUL1 E3 ubiquitin ligase deregulates mitophagy and prevents diet-induced obesity in mice
To investigate how the absence of MUL1 affects metabolic changes as reflected by gene expression.
ORGANISM(S): Homo sapiens 
2022-07-20 | GSE201725 | GEO
Increased ROS levels in mitochondrial outer membrane protein Mul1-deficient oocytes result in abnormal preimplantation embryogenesis
Obesity is a growing epidemic affecting billions of people worldwide and a major risk factor for a multitude of chronic diseases and premature mortality. Accumulating evidence suggests that mitochondria have a profound role in diet-induced obesity and the associated metabolic changes, but the molecu...
ORGANISM(S): Mus musculus 
2024-04-30 | GSE263865 | GEO
Loss of Mul1 in oocytes evoke high ROS concentration and results in abnormal embryogenesis before implantation.
ORGANISM(S): Mus musculus 
2024-07-22 | GSE242547 | GEO
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