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TranscriptomicsNeonatal antibotic prophylaxis modulates intestinal immunity and prevents necrotizing enterocolitis in preterm neonates
Caesarean-delivered preterm pigs were fed 3 d of parenteral nutrition followed by 2 d of enteral formula feeding. Antibiotics (n=11) or control saline (n=13) were given twice daily from birth to tissue collection at d 5. NEC-lesions and intestinal structure, function, microbiology and immunity marke...
ORGANISM(S): Sus scrofa 
2013-08-21 | E-GEOD-48125 | biostudies-arrayexpress
TranscriptomicsEffects of Bifidobacterium bifidum PRL2010 on gene expression in intestinal epithelial cells
Analysis of gene expression in Caco-2 intestinal epithelial cells stimulated with Bifidobacterium bifidum PRL2010. We used microarrays to investigate gene expression in intestinal epithelial cells in response to Bifidobacterium bifidum PRL2010, in particular genes involved in mucin pathways. Caco-2 ...
ORGANISM(S): Homo sapiens 
2010-10-01 | E-GEOD-21976 | biostudies-arrayexpress
TranscriptomicsThe Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses
Microbiota-induced cytokine responses participate in gut homeostasis, but the cytokine balance at steady-state and the role of individual bacterial species in setting the balance remain elusive. Using gnotobiotic mouse models, we provide a systematic analysis of the role of microbiota in the inducti...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-18056 | biostudies-arrayexpress
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