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TranscriptomicsTranscription profiling of rat cardiac myocytes and fibroblasts subjected to 24 hours of mechanical stress, or treated with a single dose of ionizing or ultraviolet radiation and allowed to recover for 24 hours
Rationale: During excessive pressure or overload, cardiac cells are subjected to increased mechanical stress. We investigate how the stress response of cardiac cells to mechanical stress can be compared to genotoxic stresses induced by DNA damaging agents. Methods: Cultures enriched for cardiomyocyt...
ORGANISM(S): Rattus norvegicus 
2007-09-18 | E-GEOD-2032 | biostudies-arrayexpress
TranscriptomicsGenome-wide SNP analysis of cutaneous squamous cell carcinomas and actinic keratoses from organ transplant recipients
The risk of developing cutaneous squamous cell carcinoma (SCC) is markedly increased in organ transplant recipients (OTRs) compared to the normal population. Next to sun exposure, the immunosuppressive regimen is an important risk factor for SCC development in OTRs. Various gene mutations (e.g. TP53...
ORGANISM(S): Homo sapiens 
2013-02-06 | E-GEOD-32969 | biostudies-arrayexpress
TranscriptomicsMolecular profiling of cutaneous squamous cell carcinomas and actinic keratoses from organ transplant recipients
The risk of developing cutaneous squamous cell carcinoma (SCC) is markedly increased in organ transplant recipients (OTRs) compared to the normal population. Next to sun exposure, the immunosuppressive regimen is an important risk factor for the development of SCC in OTRs. Various gene mutations (e....
ORGANISM(S): Homo sapiens 
2013-02-06 | E-GEOD-32628 | biostudies-arrayexpress
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