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MetabolomicsMulti-dimensional leaf phenotypes reflect root system genotype in grafted grapevine over the growing season

BACKGROUND: Modern biological approaches generate volumes of multi-dimensional data, offering unprecedented opportunities to address biological questions previously beyond reach owing to small or subtle effects. A fundamental question in plant biology is the extent to which below...

2022-01-07 | MTBLS2831 | MetaboLights
MetabolomicsUnravelling altered RNA metabolism in pancreatic cancer cells by liquid-chromatography coupling to ion mobility mass spectrometry
Ion mobility coupling to mass spectrometry facilitates an increase of resolution and chromatographic peak-capacity. Further coupling to liquid chromatography results in multi-dimensional analytical methods, especially suitable for complex matrices with structurally similar compounds. Modified nucleo...
2019-05-16 | MTBLS812 | MetaboLights
UnknownIdentification of Hetero-aggregates in Antibody Co-formulations by Multi-dimensional Liquid Chromatography Coupled to Mass Spectrometry.
Not available
S-EPMC9893218 | biostudies-literature
ProteomicsMulti-dimensional native proteomics technology for protein complex identification and topology characterization (Mud-NatPIT)
Here, we demonstrate a pilot development of multi-dimensional native proteomics technology for protein complex identification and topology characterization (Mud-NatPIT) in complex biological samples via coupling native size exclusion chromatography (SEC), online native capillary electrophoresis-mass...
ORGANISM(S): Escherichia coli 
2026-08-04 | PXD069439 | Pride
Capillary electrophoresis-mass spectrometry Protein complex identification Native proteomics Topology characterization Surface-induced dissociation 
ProteomicsDisplacement Chromatography Mode – High protein sequence coverages and identification rates for low µg-range proteomics using online 2D-LC-MS
In bottom-up proteomics, the complexity of proteomes is still a challenge. For deep proteome profiling, multi-dimensional separation strategies and large initial protein amounts are required. Here, we report on an online 2D-LC-MS/MS approach applying strong cation exchange chromatography (SCX) in di...
ORGANISM(S): Homo sapiens (Human) 
2018-10-17 | PXD008562 | Pride
Proteomics Displacement chromatography Online 2d-lc-ms 
ProteomicsMultiphasic chip performance characterization using human thyroid cancer cell line SW1736 and human plasma
Development of an online peptide fractionation system comprising a multiphasic LC chip that integrates reversed phase and strong cation exchange chromatography upstream of the MS based on the multi-dimensional protein identification technology (mudPIT). Chips were assessed in terms of chromatographi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000081545 | MassIVE
UnknownFast, comprehensive two-dimensional liquid chromatography.
Not available
S-EPMC3205947 | biostudies-literature
UnknownDevelopment, validation, and application of a multi-method for the determination of mycotoxins, plant growth regulators, tropane alkaloids, and pesticides in cereals by two-dimensional liquid chromatography tandem mass spectrometry.
Not available
S-EPMC8044062 | biostudies-literature
ProteomicsCharacterizing complex peptide mixtures using a multi-dimensional LC-MS system : Saccharomyces cerevisiae
Not available
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2012-07-26 | PRD000469 | Pride
UnknownBreath analysis by two-dimensional gas chromatography with dual flame ionisation and mass spectrometric detection - Method optimisation and integration within a large-scale clinical study.
Not available
S-EPMC6491496 | biostudies-literature
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