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TranscriptomicsCompetition between pre-mRNAs for a limiting splicing machinery drives global changes in splicing
During meiosis in yeast, global splicing efficiency increases. The mechanism for this is relief of competition for the splicing machinery by repression of intron-containing ribosomal protein genes (RPGs). Repression of RPGs with rapamycin also increases splicing efficiency in vegetative cells. Reduc...
ORGANISM(S): Saccharomyces cerevisiae 
2013-10-22 | E-GEOD-44219 | biostudies-arrayexpress
Transcriptomicsmer1D_SK1, mer2D_SK1, mer3D_SK1, spo22D_SK1, and spo70D_SK1 on expression/splicing microarrays
mer1D_SK1, mer2D_SK1, mer3D_SK1, spo22D_SK1, spo70D_SK1 late 9h meiotic time point. mer1D, mer2D, mer3D, spo22D diploid, and spo70D diploid was generated in the SK1 strain background (ATCC: MYA-2089) by PCR-mediated cassette-based gene replacement where the MER1, MER2, MER3, SPO22, or SPO70 ORF resp...
ORGANISM(S): Saccharomyces cerevisiae 
2011-04-05 | E-GEOD-24678 | biostudies-arrayexpress
Transcriptomicsume6D_BY4741 on expression/splicing microarrays
ume6D_BY4741 vegetative RNA compared to WT_BY4741 vegetative RNA. ume6D haploid was generated in the BY4741 strain background (ATCC: 201388) by PCR-mediated cassette-based gene replacement where the UME6 ORF was replaced with KANMX6, the deletion was verified by PCR. Vegetatively grown; Dye swap; Re...
ORGANISM(S): Saccharomyces cerevisiae 
2011-04-05 | E-GEOD-24680 | biostudies-arrayexpress
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