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ProteomicsOrgan-specific metabolic pathways distinguish prediabetes, type 2 diabetes and normal tissues
Defects in pancreatic islets and the progression of multi-tissue insulin resistance in combination with environmental factors are the main causes of type 2 diabetes (T2D). Mass spectrometry-based proteomics of five key-metabolic tissues on a cohort of 42 multi-organ donors provided deep coverage of ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-12 | PXD027597 | Pride
Pancreatic islets Proteomics Type 2 diabetes Serum Liver Skeletal muscle Visceral adipose tissue (vat) 
UnknownA System for Gene Expression Noise Control in Yeast.
Not available
S-EPMC6243393 | biostudies-literature
UnknownPolyphasic analyses of methanogenic archaeal communities in agricultural biogas plants.
Not available
S-EPMC2849221 | biostudies-literature
OtherComprehensive and reproducible phosphopeptide enrichment using iron immobilized metal ion affinity chromatography (Fe-IMAC) columns.
Data from ProteomeXchange, PXD ID: PXD001060. File: 00730_A11_P005652_S00_T01_R1.mzml. Published as part of Mol Cell Proteomics. 2015 Jan;14(1):205-15 . From the Abstract: {{i}} ... Current offline enrichment approaches using TiO(2), Ti, and Fe immobilized metal ion affinity chromatography (IMAC) m...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32310023168 | GPMDB
Resource Reanalysis 
UnknownA knowledge graph to interpret clinical proteomics data.
Not available
S-EPMC9110295 | biostudies-literature
ProteomicsAnalysis of oak stem lesions in Acute Oak Decline using shotgun proteomics
Acute Oak Decline (AOD) is a decline-disease currently spreading in Britain, threatening oak trees. Here, we analyze and compare the proteomes of inner bark tissue sampled from oak stems of trees symptomatic with AOD and non-symptomatic trees.
ORGANISM(S): Quercus petraea Quercus robur 
2018-02-07 | PXD004991 | Pride
Acute oak decline Metaproteomics Oak stem 
ProteomicsA systems-level insight into PHB-driven metabolic adaptation orchestrated by the PHB-binding transcriptional regulator AniA (PhaR)
Polyhydroxybutyrate (PHB) is a carbon and energy storage polymer, whose accumulation under nutrient imbalances with excess carbon is a widespread phenomenon in bacteria. PhaR is a conserved transcriptional regulator found to be associated to PHB granules in several species. Although its role in modu...
ORGANISM(S): Sinorhizobium meliloti 1021 
2025-09-01 | PXD061645 | Pride
Polyhydroxybutyrate Sinorhizobium meliloti 
UnknownInterleukin-12 signaling drives Alzheimer's disease pathology through disrupting neuronal and oligodendrocyte homeostasis.
Not available
S-EPMC12003168 | biostudies-literature
UnknownSleep deprivation leads to non-adaptive alterations in sleep microarchitecture and amyloid-β accumulation in a murine Alzheimer model.
Not available
S-EPMC12379227 | biostudies-literature
UnknownOrgan-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues.
Not available
S-EPMC9589007 | biostudies-literature
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