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Unknown25-Hydroxyvitamin D deficiency and risk of MS among women in the Finnish Maternity Cohort.
Not available
S-EPMC5634665 | biostudies-literature
ProteomicsDefining the effects of genetic variation on a proteome-wide scale
Genetic variation governs protein expression through both transcriptional and post-transcriptional processes. To investigate this relationship, we combined a multiplexed, mass spectrometry-based method for protein quantification with an emerging mouse model harboring extensive genetic variation fro...
ORGANISM(S): Mus musculus (Mouse) 
2016-06-15 | PXD002801 | Pride
Tmt Proteomics Quantitative Quantitative trait loci 
TranscriptomicsRNA-seq alignment to individualized genomes
The source of most errors in RNA sequencing (RNA-seq) read alignment is in the repetitive structure of the genome and not with the alignment algorithm. Genetic variation away from the reference sequence exacerbates this problem causing reads to be assigned to the wrong location. We developed a metho...
ORGANISM(S): Mus musculus 
2014-06-10 | E-GEOD-45684 | biostudies-arrayexpress
UnknownVitamin D as an early predictor of multiple sclerosis activity and progression.
Not available
S-EPMC4000029 | biostudies-literature
Proteomics,MultiomicsDefining the effects of genetic variation on a proteome-wide scale
Genetic variation governs protein expression through both transcriptional and post-transcriptional processes. To investigate this relationship, we combined a multiplexed, mass spectrometry-based method for protein quantification with an emerging mouse model harboring extensive genetic variation fro...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2017-11-08 | MSV000081696 | MassIVE
GenomicsGenome-wide map of H3K4me3 and PRDM9-binding in 12 day post-partum mouse spermatocytes
PRDM9, a histone methyltransferase, initiates meiotic recombination by binding DNA at recombination hotspots and directing the position of DNA double-strand breaks (DSB). The DSB repair mechanism suggests that hotspots should eventually self-destruct, yet genome-wide recombination levels remain cons...
ORGANISM(S): Mus musculus 
2015-01-13 | E-GEOD-60906 | biostudies-arrayexpress
UnknownMolecular mechanism underlying the impact of vitamin D on disease activity of MS.
Not available
S-EPMC4180413 | biostudies-literature
GenomicsGenome wide DNA methylation of Epstein-Barr virus infected immortalized normal oral keratinocytes
The oral cavity is the persistent reservoir for EBV with lifelong infection of resident epithelial and B cells. Infection of these cell types results in distinct EBV gene expression patterns that are regulated by epigenetic modifications involving DNA methylation and chromatin structure. Such regula...
ORGANISM(S): Homo sapiens 
2014-08-01 | E-GEOD-59842 | biostudies-arrayexpress
UnknownVitamin D, smoking, EBV, and long-term cognitive performance in MS: 11-year follow-up of BENEFIT.
Not available
S-EPMC7274920 | biostudies-literature
TranscriptomicsGenome wide DNA methylation and expression profiling of Epstein-Barr virus infected immortalized normal oral keratinocytes
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-08-01 | E-GEOD-59843 | biostudies-arrayexpress
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