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Long-lasting activation of T cells requires up-regulation of many genes, for example of transcription factors, cytoskeletal proteins and cell surface proteins including ion channels. An increase of ion channel density at the cell surface reflects the needs to manage increased Ca2+ influx into the ac...
ORGANISM(S): Homo sapiens 
We identified 7 CNV regions that were associated significantly with hyperlipidemia and myocardial infarction in our patients through multistage analysis (P<0.001). The inclusion criteria for enrolling patients were drawn from the Prospective Cardiovascular Munster study [http://www.ncbi.nlm.nih.gov/...
ORGANISM(S): Homo sapiens 
MicroRNA expression was assayed from bronchial epithelial cells collected via bronchoscopy from healthy current and never smoker volunteers in order to determine the effect of cigarette smoke exposure on airway epithelial microRNA expression Keywords: Global microRNA expression profiling Bronchial ...
ORGANISM(S): Homo sapiens 
Set3 complex (Set3C) binds histone H3 dimethylated at lysine 4 (H3K4me2) to mediate deacetylation of histones in 5Õ transcribed regions. To discern how Set3C affects gene expression, genome-wide transcription was analyzed in yeast undergoing a series of carbon source shifts. Deleting SET3 primarily ...
ORGANISM(S): Saccharomyces cerevisiae 
This SuperSeries is composed of the following subset Series: GSE14633: Gene expression from bronchial epithelial cell samples of current and never smokers. GSE14634: MicroRNA expression from bronchial epithelial cell samples of current and never smokers. Refer to individual Series
ORGANISM(S): Homo sapiens 
Background: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized by varying degrees of emphysematous lung destruction and small airway disease, each with distinct effects on clinical outcomes. There is little known about how microRNAs contribute specifically to the e...
ORGANISM(S): Homo sapiens 
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