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TranscriptomicsExpression data from human iPS cells and fibroblasts
DNA methylation is often inversely correlated with gene expression. We used expression microarrays to determine the relationship between DNA methylation and gene expression in 6 iPS cell lines and the fibroblasts from which they were derived. We isolated RNA from iPS cells and fibroblasts for which ...
ORGANISM(S): Homo sapiens 
2009-10-31 | E-GEOD-18226 | biostudies-arrayexpress
TranscriptomicsDNA methylation data from human iPS cells and fibroblasts
DNA methylation is often inversely correlated with gene expression. We used custom Nimblegen microarrays to determine the relationship between DNA methylation and gene expression in 6 iPS cell lines and the fibroblasts from which they were derived. We isolated genomic DNA from iPS cells and fibrobla...
ORGANISM(S): Homo sapiens 
2009-10-31 | E-GEOD-18227 | biostudies-arrayexpress
TranscriptomicsHuman iPS cells and fibroblasts
This SuperSeries is composed of the following subset Series: GSE18226: Expression data from human iPS cells and fibroblasts GSE18227: DNA methylation data from human iPS cells and fibroblasts Refer to individual Series
ORGANISM(S): Homo sapiens 
2009-10-31 | E-GEOD-18111 | biostudies-arrayexpress
TranscriptomicsDNA methylation data from non-immortalized lymphocyte samples from participants of the AGES Reykjavik Study
Genome-wide DNA methylation was studied to identify regions with extreme inter-individual variability, half of which show stability within-person, and some of which show covariation with body mass index consistently and are located in or near genes previously implicated in regulating body weight or ...
ORGANISM(S): Homo sapiens 
2010-09-14 | E-GEOD-23858 | biostudies-arrayexpress
TranscriptomicsA comprehensive methylome map of lineage commitment from hematopoietic progenitors
Epigenetic modifications must underlie lineage-specific differentiation since terminally differentiated cells express tissue-specific genes, but their DNA sequence is unchanged. Hematopoiesis provides a well-defined model of progressive differentiation in which to study the role of epigenetic modifi...
ORGANISM(S): Mus musculus 
2010-08-15 | E-GEOD-20244 | biostudies-arrayexpress
TranscriptomicsDNA methylation data from a separate set of human iPS cells and fibroblasts, and ES cells
We used custom Nimblegen microarrays to determine the DNA methylation profiles of iPS cells, ES cells, and fibroblasts. We isolated genomic DNA from iPS cells, ES cells, and fibroblasts and hybridized to custom-designed Nimblegen microarrays (CHARM arrays).
ORGANISM(S): Homo sapiens 
2010-10-20 | E-GEOD-24820 | biostudies-arrayexpress
UnknownDetection of elusive DNA copy-number variations in hereditary disease and cancer through the use of noncoding and off-target sequencing reads.
Not available
S-EPMC11023916 | biostudies-literature
ProteomicsA Multi-Omic Analysis of Human Naive CD4 T cells
Technological advances in genomics, epigenomics, transcriptomics and proteomics have enabled massively parallel measurements across thousands of genes and gene products. Such high-throughput technologies have been extensively used to carry out genome-wide studies particularly in the context of disea...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-04-04 | MSV000079624 | MassIVE
UnknownENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk.
Not available
S-EPMC10425727 | biostudies-literature
UnknownMapping the human genetic architecture of COVID-19.
Not available
S-EPMC8674144 | biostudies-literature
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