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ProteomicsIn-depth membrane proteomic study of breast cancer tissues
Proteomics on Human breast cancer tissue samples. 9 patients with high risk or 9 patiens low risk MammaPrint breast cancer. Membran fraction. Proteins were reduced, alkylated, digested with Lys-C and Trypsin, and labelled with iTRAQ4plex: 114; high risk; 115; low risk.
ORGANISM(S): Homo sapiens (Human) 
2013-01-08 | PXD000066 | Pride
Breast cancer Human Membrane protein 
ProteomicsHuman Cerebrospinal fluid LC-MSMS
Chronic Traumatic Encephalopathy (CTE) is a tauopathy that affects individuals with a history of repetitive mild traumatic brain injury, such as American football players. Initial neuropathologic changes in CTE include perivascular deposition of phosphorylated microtubule-associated protein tau (p-t...
ORGANISM(S): Homo sapiens (Human) 
2019-10-30 | PXD015358 | Pride
Cerebrospinal fluid Extracellular vesicles Lc-msmsms Chronic traumatic encephalopathy Tmt label 
ProteomicsProtein profiling of CAST.APP/PS1 mouse brain-derived Extracellular vesicles
Extracellular vesicles (EVs) are secreted by any neuronal cells in the central nervous system (CNS) for molecular clearance, cellular communications and disease spread in multiple neurodegenerative diseases, including Alzheimer’s disease (AD), although their exact molecular mechanism is poorly under...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD022349 | Pride
App/ps1 mouse Extracellular vesicles Brain tissue Lc-msmsms Tmt label 
ProteomicsHuman and mouse brain, and human cerebrospinal fluid extracellular vesicles LC-MSMS
Extracellular vesicles (EVs) are a unified terminology of membrane-enclosed vesicular species ubiquitously secreted by almost every cell type and present in all body fluids. They carry a cargo of lipids, metabolites, nucleic acids and proteins for their clearance from cells as well as for cell-to-ce...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2020-02-17 | PXD017273 | Pride
Human Cerebrospinal fluid Lc-msms Extracellular vesicles Brain tissue Mouse Tmt label 
TranscriptomicsGene expression profiles of mouse embryonic fibroblasts (MEFs), induced cardiomyocytes (iCMs) and heart
Global gene expression patterns of the iCMs shift from a MEF state toward a cardiac-like phenotype by Gata4/Mef2c/Tbx5 (GMT) or GMT/miR-133 transduction at 3, 7 and 18 days after transduction (D3, D7 and D18) MiR-133 silenced fibroblast signatures in parallel with cardiac gene activation, and Snai1 ...
ORGANISM(S): Mus musculus 
2014-07-03 | E-GEOD-56875 | biostudies-arrayexpress
TranscriptomicsGene expression profile of human cardiac fibroblasts (HCFs), induced cardiomyocytes (iCMs), and heart
Global gene expression profile of total 24460 probes in the iCMs. The gene expression shifts from a fibroblast state toward a cardiac-like phenotype by Gata4/Mef2c/Tbx5/Mesp1/Myocd (GMTMM) or GMTMM/miR-133 transduction at 7 days after transduction. MiR-133 silenced fibroblast signatures in parallel ...
ORGANISM(S): Homo sapiens 
2014-07-03 | E-GEOD-56874 | biostudies-arrayexpress
ProteomicsProteomic and phosphoproteomic data of colorectal cancer tissues and cells for Chromosome-Centric Human Proteome Project
Protein extraction and proteolytic digestion were performed using a Filter-Assisted Sample Preparation (FASP) protocol. In case of phosphopeptide enrichment immobilized Fe(III) affinity chromatography (Fe-IMAC) was performed. The peptides were fractionated using an HPLC system fitted with an SCX col...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-03-15 | MSV000079583 | MassIVE
TranscriptomicsGene expression profiles of induced cardiomyocytes(iCMs)
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-07-03 | E-GEOD-56913 | biostudies-arrayexpress
OtherDiscovery of colorectal cancer biomarker candidates by membrane proteomic analysisand subsequent verification using selected reaction monitoring and tissue microarrayanalysis
Data from ProteomeXchange, PXD ID: PXD000851. File: iTRAQ3.msf.mgf. Published as part of Mol Cell Proteomics. 2014 Mar 31 . From the Abstract: {{i}} We here performed a quantitative proteomic analysis of membrane fractions from colorectal cancer tissue to discover biomarker candidates, and then ext...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM11210027051 | GPMDB
Resource Reanalysis 
ProteomicsTissue-exudative extracellular vesicles of colorectal cancer
Freshly resected colorectal cancer tissues and adjacent normal tissues of 17 individuals were incubated in serum-free medium. Extracellular vesicles were isolated from the medium with ultracentrifugation method.
ORGANISM(S): Homo Sapiens (human) 
2021-03-06 | PXD020439 | JPOST Repository
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