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ProteomicsProteomics profiling of research models for studying pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with a five-year survival rate of 10-15% due to late-stage diagnosis and limited efficacy of existing treatments. This study utilized proteomics-based system modelling to generate multimodal datasets from various re...
ORGANISM(S): Mus musculus (Mouse) 
2024-12-18 | PXD057829 | Pride
Murine pancreatic exocrine organoids 
ProteomicsProteomics profiling of research models for studying pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with a five-year survival rate of 10-15% due to late-stage diagnosis and limited efficacy of existing treatments. This study utilized proteomics-based system modelling to generate multimodal datasets from various re...
ORGANISM(S): Mus musculus (Mouse) 
2024-12-18 | PXD057888 | Pride
Murine pdac organoids 
ProteomicsEngineering Palmitoylated G-Quadruplex Aptamers to Target STAT3 and Overcome Therapeutic Resistance in Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies owing to extensive therapeutic resistance and limited treatment options. Increasing evidence indicates that activation of the IL-6–JAK–STAT3 pathway represents a major adaptive survival mechanism that promotes resistance ...
ORGANISM(S): Mus musculus (Mouse) 
2026-08-27 | PXD082487 | Pride
Aptamer  stat3  kras  g4 
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