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MetabolomicsDivalent Aptamer-mediated Clustering for Extracellular Vesicle Separation
Extracellular vesicles (EVs) are important mediators of intercellular communication and promising sources of diagnostic and therapeutic biomarkers, yet effective EV isolation remains challenging due to trade-offs among yield, purity, and adaptability across biofluids. Here, we introduce divalent apt...
2026-05-04 | MTBLS14425 | MetaboLights
TranscriptomicsACE-Scan of the ATP DNA aptamer on various density Gen2 DNA microarrays
The experiments were carried out to map the ligand binding landscape of various DNA and RNA duplexed aptamer families. Duplexed Aptamer (DA) constructs were engineered from (i) natural and synthetic DNA and RNA aptamers and (i) synthetic oligonucleotide aptamer-complementary elements synthesized on ...
ORGANISM(S): synthetic construct 
2017-12-20 | E-MTAB-6375 | biostudies-arrayexpress
TranscriptomicsACE-Scan of the cocaine DNA aptamer on 10^12 Gen1 DNA microarray
The experiments were carried out to map the ligand binding landscape of various DNA and RNA duplexed aptamer families. Duplexed Aptamer (DA) constructs were engineered from (i) natural and synthetic DNA and RNA aptamers and (i) synthetic oligonucleotide aptamer-complementary elements synthesized on ...
ORGANISM(S): synthetic construct 
2017-12-20 | E-MTAB-6377 | biostudies-arrayexpress
TranscriptomicsACE-Scan of the ATP RNA aptamer on 10^12 Gen1 DNA microarray
The experiments were carried out to map the ligand binding landscape of various DNA and RNA duplexed aptamer families. Duplexed Aptamer (DA) constructs were engineered from (i) natural and synthetic DNA and RNA aptamers and (i) synthetic oligonucleotide aptamer-complementary elements synthesized on ...
ORGANISM(S): synthetic construct 
2017-12-20 | E-MTAB-6376 | biostudies-arrayexpress
TranscriptomicsACE-Scan of the ATP DNA aptamer on 10^12 density Gen1 DNA microarray
The experiments were carried out to map the ligand binding landscape of various DNA and RNA duplexed aptamer families. Duplexed Aptamer (DA) constructs were engineered from (i) natural and synthetic DNA and RNA aptamers and (i) synthetic oligonucleotide aptamer-complementary elements synthesized on ...
ORGANISM(S): synthetic construct 
2017-12-20 | E-MTAB-6374 | biostudies-arrayexpress
TranscriptomicsACE-Scan of the natural add riboswitch aptamer on 10^10 Gen1 DNA microarrays with varying buffer temperatures and Mg2+ cation concentrations
The experiments were carried out to map the ligand binding landscape of various DNA and RNA duplexed aptamer families. Duplexed Aptamer (DA) constructs were engineered from (i) natural and synthetic DNA and RNA aptamers and (i) synthetic oligonucleotide aptamer-complementary elements synthesized on ...
ORGANISM(S): synthetic construct 
2017-12-20 | E-MTAB-6380 | biostudies-arrayexpress
TranscriptomicsACE-Scan of the thrombin DNA aptamer on 10^10 Gen1 DNA microarrays with sodium and potassium buffers in two colors.
The experiments were carried out to map the ligand binding landscape of various DNA and RNA duplexed aptamer families. Duplexed Aptamer (DA) constructs were engineered from (i) natural and synthetic DNA and RNA aptamers and (i) synthetic oligonucleotide aptamer-complementary elements synthesized on ...
ORGANISM(S): synthetic construct 
2017-12-20 | E-MTAB-6378 | biostudies-arrayexpress
ProteomicsAptamer Affinity Mass Spectrometry
Antibody-based affinity purification of macromolecular complexes has revolutionized the study of protein-protein interactions. Here, we present AptA-MS (Aptamer Affinity – Mass Spectrometry), a robust strategy using a specific, high-affinity RNA aptamer against GFP to identify novel interactors of a...
ORGANISM(S): Homo sapiens (Human) 
2020-06-17 | PXD015620 | Pride
Hct116 Aptamer Rna aptamer Heat shock factor S2 
ProteomicsFacile Discovery of Cell-surface Protein Targets of Cancer Cell Aptamers
Cancer biomarker discovery constitutes a frontier in cancer research. In recent years, cell-binding aptamers have become useful molecular probes for biomarker discovery. However, there are few successful examples, and the critical barrier resides in the identification of the cell-surface protein tar...
ORGANISM(S): Homo sapiens (Human) 
2022-02-28 | PXD002480 | Pride
Ms Aptamer Aptamer Biomarker 
ProteomicsDivalent Aptamer-mediated Clustering for Extracellular Vesicle Separation
Extracellular vesicles (EVs) are important mediators of intercellular communication and promising sources of diagnostic and therapeutic biomarkers, yet effective EV isolation remains challenging due to trade-offs among yield, purity, and adaptability across biofluids. Here, we introduce divalent apt...
ORGANISM(S): Homo Sapiens 
PXD078053 |
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