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TranscriptomicsGene expression data of brown-like adipocytes from Lgr4 homozygous mutant SVF
Obesity has become a global health problem. Brown adipose tissue (BAT), specialized for energy expenditure through thermogenesis, potently counteracts obesity. Recently, BAT is also identified in human adults. We found that Lgr4 homozygous mutant (Lgr4m/m) mice display reduced adiposity and exhibit ...
ORGANISM(S): Mus musculus 
2013-11-07 | E-GEOD-47760 | biostudies-arrayexpress
TranscriptomicsTranscription profile of SSEA-3-positive population of MSCs
Microarray analysis of the gene expression profile of SSEA-3-positive human adipose-derived MSCs were performed. Liposuction aspirates were obtained from the abdomen and thighs. Stromal vascular fraction (SVF) was isolated from the aspirated fat. Muse cells that express human SSEA-3 were collected f...
ORGANISM(S): Homo sapiens 
2015-01-07 | E-GEOD-55526 | biostudies-arrayexpress
Transcriptomics3’RNA-seq of murine fresh and expanded ASPCs
To characterize murine ASPCs we performed bulk RNA-seq (BRB-seq, Alpern et al., 2019) of total, CD142− and CD142+ (Aregs) mouse adipose stem and progenitor cells (ASPCs). ASPCs were collected as Lin− (CD31− CD45− TER119−) CD29+ CD34+ SCA1+ cells of the mouse subcutaneous stromal vascular fraction us...
ORGANISM(S): Mus musculus 
2022-07-04 | E-MTAB-10179 | biostudies-arrayexpress
ProteomicsComparative secretome analysis of primary murine white and brown adipocytes
The adipose organ, including white and brown adipose tissues, is an important player in systemic energy homeostasis, storing excess energy in form of lipids while releasing energy upon various energy demands. Recent studies have demonstrated that white and brown adipocytes also function as endocrine...
ORGANISM(S): Mus musculus (Mouse) 
2018-09-04 | PXD009280 | Pride
Brown adipocytes Adrenergic stimulation White adipocytes Secretome Murine svf cells 
UnknownGender and age-related cell compositional differences in C57BL/6 murine adipose tissue stromal vascular fraction.
Not available
S-EPMC6224190 | biostudies-literature
TranscriptomicsThe beating cluster of adipose tissue-derived stromal cells
Adipose tissue-derived stromal vascular fraction (Ad-SVF) contains stem cells and rarely transdifferentiate into spontaneously beating cardiomyocyte-like cells (beating CMs). However, the factors that regulate the differentiation of Ad-SVF into the cardiac lineage is unknown. We developed a simple c...
ORGANISM(S): Mus musculus 
2021-01-21 | GSE154301 | GEO
TranscriptomicsNext generation sequencing analysis of microRNAs in brown preadipocytes and in vitro differentiated mature brown fat cells
We performed a genome-wide deep sequencing analysis of the microRNAs abundant in mesenchymal stem cells (MSCs) derived from murine brown adipose tissue and in in vitro differentiated mature brown adipocytes. Several microRNAs were identified as differentially regulated when comparing datasets from M...
ORGANISM(S): Mus musculus 
2013-05-28 | E-GEOD-45499 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA-seq of de-differentiated mammary adipocytes during lactation
Adipose tissue in the mammary gland undergoes dramatic remodeling during reproduction. Adipocytes are replaced by mammary alveolar structures during pregnancy and lactation, then reappear upon weaning. Here, we reveal that adipocytes in the mammary gland de-differentiate into Pdgfrα+ preadipocyte- a...
ORGANISM(S): Mus musculus 
2018-06-17 | E-MTAB-6818 | biostudies-arrayexpress
UnknownMyocyte-specific enhancer factor 2c triggers transdifferentiation of adipose tissue-derived stromal cells into spontaneously beating cardiomyocyte-like cells.
Not available
S-EPMC7810870 | biostudies-literature
UnknownDelivery of Human Stromal Vascular Fraction Cells on Nanofibrillar Scaffolds for Treatment of Peripheral Arterial Disease.
Not available
S-EPMC7380169 | biostudies-literature
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