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TranscriptomicsProgression of KRas^G12D;Rosa26-MYC tumours to invasive disease
The aim of the study was to investigate gene expression tumour progression of KRas*/MYC driven lung tumours from adenocarcinoma in situ to invasive disease.
ORGANISM(S): Mus musculus 
2018-06-01 | E-MTAB-6432 | biostudies-arrayexpress
MetabolomicsGNPS - Plant tribe Myoporeae: 291 species and subspecies
Paper title: Navigating through chemical space and evolutionary time across the Australian continent in plant genus Eremophila. Author List: Oliver Gericke, Rachael M. Fowler, Allison M. Heskes, Michael J. Bayly, Susan J. Semple, Chi P. Ndi, Dan Stark, Claus J. Loland, Daniel J. Murphy, Bevan J....
ORGANISM(S): Eremophila <angiosperm> (ncbitaxon:255893) Diocirea Bontia Daphnoides (ncbitaxon:255891) Myoporum (ncbitaxon:57115) Calamphoreus Inflatus Myoporeae (ncbitaxon:216811) Glycocystis 
2020-12-29 | MSV000086644 | GNPS
TranscriptomicsRNA-seq to investigate impact of treatment of KRAS mutant A549 lung adenocarcinoma cells with the multi-ERBB inhibitor Neratinib
KRAS mutation is widely presumed to confer independence from upstream RTK signalling, however emerging evidence from mouse models of lung cancer suggests that ERBB RTKs may amplify signalling through RAS isoforms and participate in mutant RAS-driven lung cancer. This is one of 3 datasets where we e...
ORGANISM(S): Homo sapiens 
2018-06-01 | E-MTAB-6483 | biostudies-arrayexpress
TranscriptomicsRNA-seq to investigate impact of treatment of KRAS mutant NCI-H2009 lung adenocarcinoma cells with the multi-ERBB inhibitor Neratinib
KRAS mutation is widely presumed to confer independence from upstream RTK signalling, however emerging evidence from mouse models of lung cancer suggests that ERBB RTKs may amplify signalling through RAS isoforms and participate in mutant RAS-driven lung cancer. This is one of 3 datasets where we e...
ORGANISM(S): Homo sapiens 
2018-06-01 | E-MTAB-6486 | biostudies-arrayexpress
TranscriptomicsRNA-seq to investigate impact of treatment of KRAS mutant NCI-H358 lung adenocarcinoma cells with the multi-ERBB inhibitor Neratinib
KRAS mutation is widely presumed to confer independence from upstream RTK signalling, however emerging evidence from mouse models of lung cancer suggests that ERBB RTKs may amplify signalling through RAS isoforms and participate in mutant RAS-driven lung cancer. This is one of 3 datasets where we e...
ORGANISM(S): Homo sapiens 
2018-06-01 | E-MTAB-6485 | biostudies-arrayexpress
GenomicsBIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues
C-MYC (henceforth MYC) is one of the most frequently overexpressed oncogenes in human cancer and even modestly deregulated MYC expression can initiate ectopic proliferation in many post-mitotic, terminally differentiated cell types in vivo. Metazoan organisms have consequently evolved a number of me...
ORGANISM(S): Homo sapiens 
2015-05-18 | E-GEOD-59001 | biostudies-arrayexpress
UnknownSmall-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory Axis.
Not available
S-EPMC4670040 | biostudies-literature
MetabolomicsGNPS - GNPS Paper Novel Stenothricin Analog Supporting Information.
Mass spectrometry data, NMR, and sequencing data in support of the discovery of stenothricin-GNPS. Secondary metabolite production of Streptomyces Roseosporus was compared against Streptomyces DSM5940.
ORGANISM(S): Streptomyces (ncbitaxon:1883) 
2015-07-30 | MSV000079204 | GNPS
UnknownHaptoglobin genotype and outcome after spontaneous intracerebral haemorrhage.
Not available
S-EPMC7612606 | biostudies-literature
UnknownVitrectomy outcomes in eyes with diabetic macular edema and vitreomacular traction.
Not available
S-EPMC2911350 | biostudies-literature
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