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TranscriptomicsRNA-seq analysis of skeletal muscle-specific Crls1 knockout (MUCKO) mice reveals fiber-type-dependent transcriptional remodeling in Soleus and EDL
Cardiolipin (CL) is a mitochondria-specific phospholipid essential for inner membrane architecture and respiratory chain function. To determine how loss of CL biosynthesis affects skeletal muscle transcriptional programs in a fiber-type-dependent manner, we generated skeletal muscle-specific Crls1 k...
ORGANISM(S): Mus musculus 
2026-08-08 | E-MTAB-17333 | biostudies-arrayexpress
GenomicsFed and fasted skeletal muscle of wildtype and PGC-1beta muscle specific knockout mice
Fed and fasted skeletal muscle of wildtype and PGC-1beta muscle specific knockout mice
PRJNA868289 | ENA
GenomicsCharacterization of novel endothelial-specific and smooth-muscle specific Poldip2 knockout mice
Characterization of novel endothelial-specific and smooth-muscle specific Poldip2 knockout mice
PRJNA698620 | ENA
TranscriptomicsDifferential gene expression in mouse skNAC knockout heart at E11.5
Targeted deletion of skNAC in mice resulted in early embryonic lethality with cardiac defects. In order to investigate the molecular mechanism of the cardiac defect, we designed the microarray comparing gene expression of the mutant E11.5 heart to wild type E11.5 heart. Keywords: genetic modificat...
ORGANISM(S): Mus musculus 
2010-11-19 | E-GEOD-5841 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of Ncor1 muscle-specific knockout and PGC-1alpha muscle-specific transgenic skeletal muscle
In the present study we have studied the mechanistic and functional aspects of NCoR1 function in mouse skeletal muscle. NCoR1 muscle-specific knockout mice exhibited an increased oxidative metabolism. Global gene expression analysis revealed a high overlap between the effects of NCoR1 deletion and p...
ORGANISM(S): Mus musculus 
2013-01-08 | E-GEOD-40439 | biostudies-arrayexpress
GenomicsAnalysis of gastrocnemius muscle from chow-fed control and skeletal muscle specific Cpt1b knockout mice
Analysis of gastrocnemius muscle from chow-fed control and skeletal muscle specific Cpt1b knockout mice
PRJNA419145 | ENA
GenomicsTranscriptome analysis of Rev-erbs skeletal muscle specific knockout muscles and WT muscles
Transcriptome analysis of Rev-erbs skeletal muscle specific knockout muscles and WT muscles
PRJNA1050255 | ENA
GenomicsExpression profiling of type II skeletal muscle fibers from wild-type mice, myofiber-specific and satellite cell-specific Rrm2b knockout models
Expression profiling of type II skeletal muscle fibers from wild-type mice, myofiber-specific and satellite cell-specific Rrm2b knockout models
PRJEB50062 | ENA
no omics definedTranscription profiling by array of mouse motor nerve-stimulated and the contralateral control tabialis anterior muscles
Exercise induces skeletal muscle adaptation, and the p38 mitogen-activated protein kinase signaling pathway is thought to play an important role in the adaptive processes. We have obtained new evidence that the gamma isoform of p38 is required for exercise-induced metabolic adaptation in skeletal mu...
ORGANISM(S): Mus musculus 
2010-03-03 | E-GEOD-17620 | biostudies-arrayexpress
GenomicsNext Generation Sequencing Facilitates Quantitative Analysis of Transcriptomes of Skeletal Muscle-Specific Akt Knockout Mice
Next Generation Sequencing Facilitates Quantitative Analysis of Transcriptomes of Skeletal Muscle-Specific Akt Knockout Mice
PRJNA818289 | ENA
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