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This project aims to elucidate the molecular mechanism underlying the stable golden-yellow phenotype and enhanced protein accumulation in an Auxenochlorella pyrenoidosa mutant (CX41) generated by ARTP mutagenesis. Through comparative analysis between the wild-type (FACHB-9) and mutant s...

2025-12-26 | MTBLS13574 | MetaboLights
Muscle tissues from GMPPB mutant mouse model and control mice were collected, untargeted metabolomics was performed via LC-MS (positive/negative HILIC), differential metabolites were identified to explore the mechanismof GMPPB in muscular dystrophy.
2026-02-03 | MTBLS10214 | MetaboLights
This study aimed to identify differentially expressed metabolites between Vd991 and VdGGCT knockout mutant strains using liquid chromatography-mass spectrometry (LC-MS). A total of 6 samples, including both Vd991 and VdGGCT knockout mutant groups, were analyzed to explore metabolic changes and disco...
2026-05-11 | MTBLS14397 | MetaboLights
Poly (ADP-ribose) polymerase inhibitors (PARPi) are widely used as targeted therapies against breast cancers with BRCA mutations. However, the development of resistance to PARPi poses a significant challenge for long-term efficacy of these therapies, warranting further understanding of mechanisms of...
2026-05-11 | MTBLS12109 | MetaboLights
Not available
ORGANISM(S): Ruegeria pomeroyi 
Not available
ORGANISM(S): Escherichia coli 
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ORGANISM(S): Arabidopsis thaliana 
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ORGANISM(S): Plasmodium falciparum;Homo sapiens 

The Unfolded Protein Response (UPR) is a retrograde, ER-to-nucleus, signalling pathway which is conserved across kingdoms. In plants, it contributes to development, reproduction, immunity and tolerance to abiotic stress. This metabolomic dataset was produced from 14-day-old Arabidopsis thaliana s...

2024-12-02 | MTBLS10096 | MetaboLights
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