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ProteomicsStructure and molecular assembly of a MuvB transcription factor complex with the nucleosome
The core cell cycle machinery genes are transcriptionally regulated by the MuvB family of protein complexes in a cell cycle specific manner. During cell cycle exit in quiescence or senescence, the DREAM complex, which is the repressive form of MuvB, directs transcriptional repression of cell cycle g...
ORGANISM(S): Homo sapiens (Human) 
2022-08-17 | PXD031421 | Pride
Muvb Crosslinking 
GenomicsGenome-wide binding profiles of the B-Myb-MuvB complex in HeLa cells
To identify genomic regions bound by B-Myb and LIN9 (a subunit of the MuvB complex), we performed ChIP-Sequencing (ChIP-Seq) using chromatin from proliferating HeLa cells in which we can detect a robust association between B-Myb and subunits of the MuvB complex. This analysis allowed us identify lat...
ORGANISM(S): Homo sapiens 
2012-01-25 | E-GEOD-27030 | biostudies-arrayexpress
UnknownStructure and function of MuvB complexes.
Not available
S-EPMC9201786 | biostudies-literature
GenomicsDrosophila Myb-MuvB/dREAM
Drosophila Myb-MuvB/dREAM
PRJNA102609 | ENA
UnknownStructural mechanism of Myb-MuvB assembly.
Not available
S-EPMC6176624 | biostudies-literature
TranscriptomicsTranscription profiling of Drosophila Myb-MuvB/dREAM
Myb-MuvB (MMB)/dREAM is a nine subunit complex first described in Drosophila as a repressor of transcription, dependent upon E2F2 and the RBFs. Myb, an integral member of MMB, curiously plays no role in the silencing of the test genes previously analyzed. Moreover, Myb plays an activating role in DN...
ORGANISM(S): Drosophila melanogaster 
2008-06-16 | E-GEOD-8751 | biostudies-arrayexpress
GenomicsGenome-wide binding profiles of the B-Myb-MuvB complex in HeLa cells
To identify genomic regions bound by B-Myb and LIN9 (a subunit of the MuvB complex), we performed ChIP-Sequencing (ChIP-Seq) using chromatin from proliferating HeLa cells in which we can detect a robust association between B-Myb and subunits of the MuvB complex. This analysis allowed us identify lat...
ORGANISM(S): Homo sapiens 
2012-01-25 | GSE27030 | GEO
UnknownStructure of a nucleosome-bound MuvB transcription factor complex reveals DNA remodelling.
Not available
S-EPMC9424243 | biostudies-literature
UnknownThe MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes.
Not available
S-EPMC8792015 | biostudies-literature
GenomicsDrosophila Myb-MuvB/dREAM (ChIP-chip data)
Myb-MuvB (MMB)/dREAM is a nine subunit complex first described in Drosophila as a repressor of transcription, dependent upon E2F2 and the RBFs. Myb, an integral member of MMB, curiously plays no role in the silencing of the test genes previously analyzed. Moreover, Myb plays an activating role in DN...
ORGANISM(S): Drosophila melanogaster 
2007-11-14 | GSE9087 | GEO
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