Mycobacterium tuberculosis h37rv

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Unknown (840)
Transcriptomics (598)
Genomics (540)
Proteomics (204)
Metabolomics (32)
Other (8)
Models (5)
Methylation profiling (1)
Multiomics (1)

Organisms

Mycobacterium tuberculosis (270)
Mycobacterium tuberculosis H37Rv (248)
Homo sapiens (97)
Mus musculus (75)
Mycobacterium tuberculosis CDC1551 (17)
Mycolicibacterium smegmatis MC2 155 (7)
Mycobacterium tuberculosis H37Ra (6)
Mycobacterium tuberculosis str. Erdman = ATCC 35801 (5)
Mycobacterium tuberculosis variant bovis (5)
Thermus thermophilus HB8 (4)
Oryctolagus cuniculus (4)
Mycobacterium avium subsp. paratuberculosis (3)
Macaca fascicularis (3)
Mycobacterium tuberculosis variant bovis BCG (3)
Mycolicibacterium smegmatis (3)
Mycobacterium tuberculosis variant bovis BCG str. Pasteur 1173P2 (2)
Rattus norvegicus (2)
Macaca mulatta (2)
Escherichia coli (2)
Cavia porcellus (1)
Staphylococcus aureus (1)
Enterococcus faecalis (1)
Acinetobacter baumannii (1)
Corynebacterium glutamicum ATCC 13032 (1)
Mycobacterium canetti (1)
Mycobacterium tuberculosis HN878 (1)
Mycobacterium marinum E11 (1)
Mycobacterium marinum M (1)
Mycobacterium avium subsp. paratuberculosis K-10 (1)
Mycobacterium marinum (1)

Organisms

Mycobacterium tuberculosis H37Rv (169)
Mycobacterium tuberculosis (129)
Mus musculus (52)
Homo sapiens (33)
Mycobacterium tuberculosis H37RvSiena (2)
Mycobacterium tuberculosis H37Ra (2)
Macaca mulatta (2)
Mycobacterium tuberculosis IAR2 (1)
Mycobacterium tuberculosis H37RvMA (1)
Mycobacterium tuberculosis H37RvLP (1)
Mycobacterium tuberculosis EAI5 (1)
Mycobacterium tuberculosis H37RvCO (1)
Mycobacterium tuberculosis CAS/NITR204 (1)
Mycobacterium tuberculosis H37RvJO (1)
Mycobacterium tuberculosis H37RvHA (1)
Mycobacterium tuberculosis str. Haarlem/NITR202 (1)
Mycobacterium tuberculosis H37Rv_2009 (1)
Mycobacterium tuberculosis Tn11:H37Rv (1)
Mycobacterium tuberculosis EAI5/NITR206 (1)
Mycobacterium tuberculosis str. Beijing/NITR203 (1)
Mycobacterium tuberculosis CDC1551 (1)
Mycobacterium tuberculosis subsp. tuberculosis (1)
Mycobacterium (1)
Mycobacterium tuberculosis variant bovis BCG (1)
Escherichia coli K-12 (1)
Mycobacterium tuberculosis variant bovis BCG str. Tokyo 172 (1)
Mycolicibacterium smegmatis (1)
mouse gut metagenome (1)
Bos taurus (1)
Danio rerio (1)

Repository

ENA (501)
biostudies-arrayexpress (388)
geo (267)
pride (130)
MassIVE (27)
MetaboLights (15)
MetabolomicsWorkbench (15)
PeptideAtlas (11)
iProX (8)
PAXDB (7)
jPOST (5)
PanoramaPublic (5)
BioModels (4)
EGA (2)
GNPS (2)
Cell Collective (1)
EVA (1)

Tissue

Cell culture (18)
Macrophage (12)
Cultured cells (9)
Bacterial cells (6)
Blood serum (4)
Prokaryotic cell (4)
Cell line cell (3)
Cell suspension culture (3)
Primary cell (3)
Blood plasma (2)
Cell lysate (2)
Dendritic cell (2)
Blood (1)
Bronchoalveolar lavage (1)
Monocyte (1)
Protein (1)
Response to bacterium (1)
Spleen (1)
T cell (1)
Whole body (1)

Disease

Tuberculosis (33)
Tuberculosis (16)
Pulmonary tuberculosis (12)
Non-diabetic (1)
Cystic fibrosis (1)
Extrapulmonary tuberculosis (1)
Lymph node tuberculosis (1)
Mixed disorder as reaction to stress (1)

Technology Type

Mass Spectrometry (145)
Shotgun proteomics (70)
Bottom-up proteomics (18)
ESI (15)
Data-dependent acquisition (15)
Data-independent acquisition (11)
Mass spectrometry (10)
Affinity purification coupled with mass spectrometry proteomics (8)
SWATH MS (7)
Top-down proteomics (7)
Mass spectrometry assay (5)
Gel-based experiment (5)
Affinity proteomics (2)
Immunopeptidomics (2)
All-ion fragmentation (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
SRM/MRM (1)

Instrument Platform

Illumina NovaSeq 6000 (13)
NextSeq 500 (11)
Illumina HiSeq 2000 (8)
Illumina NovaSeq X (7)
Illumina HiSeq 2500 (7)
Chemostat (3)
Bioanalyser (3)
Illumina MiSeq (3)
NextSeq 550 (3)
Nanodrop N1000 spectrophotometer (2)
Bellco roll-in incubator (2)
Variable Atmosphere Incubator (2)
NA (2)
Illumina DNA Prep sample preparation kits (Illumina Inc., San Diego, CA, USA). Final libraries concentrations and size were assessed with Quant-IT DNA Assay Kit and Agilent 4200 Tapestation System (Agilent Technologies, Milan, Italy), (1)
QIAamp DNA minikit, Qiagen, Germany (1)
Rstudio (1)
Microbeads (1)
GeneChip Instrument System (1)
Affymetrix mouse gene 1.0 ST arrays (1)
Qubit 2.0, Agilent 2100 (1)
Affymetrix 428 (1)
Axon 4000B scanner (1)
Anaerobic workstation with airlock (1)
Agilent 2100 Bioanalyzer (1)
ScanArray 5000 [PerkinElmer] (1)
Illumina Genome Analyzer IIx (1)
NanoDrop (1)
Generation III Array Scanner [Amersham] (1)
None (1)
NextSeq 2000 (1)

Publication Date

2013 (75)
2014 (71)
2010 (67)
2018 (60)
2026 (53)
2012 (53)
2022 (46)
2016 (45)
2015 (44)
2025 (43)
2021 (41)
2023 (32)
2024 (31)
2011 (31)
2008 (30)
2019 (29)
2009 (28)
2007 (28)
2020 (24)
2017 (24)
2005 (5)
2006 (4)
2004 (2)

UNIPROT ID/AC

35KD_MYCTU (5)
A85A_MYCTU (5)
A85B_MYCTU (5)
A85C_MYCTU (5)
ACDP_MYCTU (5)
ACNA_MYCTU (5)
I6X8D2 (1)
P9WPB3 (1)
Q79FX8 (1)
P0CH91 (1)
Q79FX6 (1)
P9WPB1 (1)
P9WQD9 (1)
P9WQD7 (1)
P9WGR1 (1)
O53580 (1)
P9WNG3 (1)
I6Y778 (1)
P9WGR9 (1)
P9WGT3 (1)
P9WNG5 (1)
P9WNZ3 (1)
P9WNZ7 (1)
P9WPB5 (1)
P9WQD3 (1)
P9WQH7 (1)
O53578 (1)
P9WQH9 (1)
P96890 (1)
P95029 (1)

CHEBI ID

CHEBI:113592 (1)
CHEBI:389573 (1)
CHEBI:8938081 (1)
CHEBI:29358 (1)
CHEBI:6798184 (1)
CHEBI:211579 (1)
CHEBI:5696069 (1)
CHEBI:8878982 (1)
CHEBI:5632460 (1)
CHEBI:8869363 (1)
CHEBI:113593 (1)
CHEBI:25438 (1)
CHEBI:25436 (1)
CHEBI:25437 (1)
CHEBI:44520 (1)
CHEBI:24712 (1)
CHEBI:22323 (1)
CHEBI:33249 (1)
CHEBI:17087 (1)
CHEBI:25134 (1)
CHEBI:23916 (1)
CHEBI:22221 (1)
CHEBI:43176 (1)
CHEBI:3108 (1)
CHEBI:22882 (1)
CHEBI:13905 (1)
CHEBI:41236 (1)
CHEBI:22884 (1)
CHEBI:14405 (1)
CHEBI:2458 (1)

Metabolite Name

Glycine (2)
Thymine (2)
L-Proline (2)
Succinic acid (2)
Citrate (2)
Alpha-ketoglutarate (2)
Methylcitrate (1)
Mycothiol (1)
Ergothioneine(1+) (1)
Acetyl-CoA_HMDB0001206 (1)
FAD_HMDB0001248 (1)
Coenzyme A_HMDB0001423 (1)
NADP_HMDB0000217 (1)
Stachyose_HMDB0003553 (1)
NADH_HMDB0001487 (1)
NAD_HMDB0000902 (1)
Uridine diphosphate-N-acetylglucosamine_HMDB0000290 (1)
Guanosine diphosphate mannose_HMDB0001163 (1)
Uridine diphosphate glucose_HMDB0000286 (1)
Taurocholic acid_HMDB0000036 (1)
Adenosine triphosphate_HMDB0000538 (1)
Raffinose_HMDB0003213 (1)
Taurodeoxycholic acid_HMDB0000896 (1)
Deoxycholic acid glycine conjugate_HMDB0000631 (1)
Adenosine diphosphate_HMDB0001341 (1)
Sucrose 6-Phosphate_No HMDB data (1)
Cholic acid_HMDB0000619 (1)
3-Oxocholic acid_HMDB0000502 (1)
Uridine 5'-diphosphate_HMDB0000295 (1)
Deoxycholic acid_HMDB0000626 (1)

First Public Date

2014 (97)
2025 (45)
2018 (45)
2026 (42)
2024 (38)
2022 (34)
2013 (34)
2023 (30)
2021 (29)
2020 (26)
2019 (25)
2017 (23)
2015 (21)
2016 (12)

Modelling Approach

Constraint-based model (2)

Lab affiliation

Professor, Microbiology, Immunology, and Pathology Mycobacteria Research Laboratories Scientific Director, Rocky Mountain Regional Biocontainment Laboratory Editor-in-chief, BMC Mycobacteria (4)
Massachusetts Institute of Technology (3)
Colorado State University (2)
Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town (2)
ETH Zurich (2)
Farnusch Kaschani, Analytics Core Facility Essen (ACE), Chemische Biologie, Universität Duisburg-Essen, ZMB, Germany (2)
Global Health Institute, EPFL, Lausanne, Switzerland (2)
Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (2)
Rutgers Robert Wood Johnson Medical School Department of Biochemistry and Molecular Biology (2)
Shanghai Center for Systems Biomedicine Shanghai Jiao Tong University (2)
1 Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, PR China 2 Department of Microbiology and Immunology, Tongji University School of Medicine, Shanghai 200049, PR China 3 Clinical Translation Research Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China. (1)
1Departments of Medicine & 2Pathology, Case Western Reserve University and University Hospitals Case Medical Center; 3Department of Molecular Biology & Microbiology Case Western Reserve University School of Medicine, Cleveland, Ohio 44106,USA. (1)
A.N. Bach Institute of Biochemistry, Federal Research Centre ‘Fundamentals of Biotechnology’ of the Russian Academy of Sciences, Leninsky pr., 33, 119071, Moscow, Russia (1)
Aix-Marseille Univ, CNRS, LISM, IMM FR3479, 13009 Marseille, France (1)
Aix-Marseille Univ, Inserm, CNRS, Institut Paoli-Calmettes, CRCM, Marseille Protéomique (1)
Analytics Core Facility Essen (ACE), Chemische Biologie, Universität Duisburg-Essen, ZMB, Germany (1)
Assistant Professor Ramalingaswami Fellow Translational Health Science and Technology Institute NCR Biotech Science Cluster 3rd Milestone, Faridabad - Gurgaon Expressway PO box # 04 FARIDABAD 121001, India (1)
Associate Professor School of Life Sciences University of Hawaii at Manoa (1)
Associate Professor, Mycobacteria Research Laboratories Dept of Microbiology, Immunology,& Pathology (http://www.cvmbs.colostate.edu/DirectorySearch/Search/MemberProfile/CVMBS/3607) Associate Director, Research Integrity and Compliance Review Office (http://ricro.colostate.edu/) Colorado State University (1)
Australian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia (1)
Boston Children's Hospital (1)
Boston Children's Hospital | Harvard Medical School (1)
CNRS-IPBS Immunomodulation By Mycobacterial Lipids and Glycoconjugates 205 route de Narbonne 31077 Toulouse cedex 4 (1)
CSIR-CCMB (1)
Centro de Pesquisas em Biologia Molecular e Funcional (CPBMF), Instituto Nacional de Ciência e Tecnologia em Tuberculose (INCT-TB), Programa de Pós-Graduação em Biologia Celular e Molecular - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil (1)
Charles Perkins Centre, School of Medical Sciences, University of Sydney, Sydney, Australia. (1)
Chinese Center for Disease Control and Prevention (1)
DST-NRF Center for Excellence in Biomedical TB research south African Medical Research Council Center for Tuberculosis Research Division of Molecular Biology and Human Genetics Department of Biomedical Science Faculty of Medicine and Health Science Stellenbosch University Cape Town South Africa (1)
DST/NRF Centre of Excellence for Biomedical Tuberculosis Research/South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa (1)
Department of Biochemistry and Molecular Biology, Rutgers University (1)

IsPrivate

False (4)

Model Flag

Non Kinetic (4)

Submitter Keywords

FROG (2)

Classification

bacteria (321)

Study type

Transcription profiling by array (274)
RNA-seq of coding RNA (42)
Unknown experiment type (10)
ChIP-seq (10)
DNA-seq (8)
Proteomic profiling by array (7)
Other (6)
RNA-seq of total RNA (6)
ChIP-chip by tiling array (3)
Transcription profiling by tiling array (3)
One-color microarray (2)
High-throughput sequencing (2)
Human - One-color microarray (2)
RIP-seq (2)
MicroRNA profiling by array (2)
RNA-seq of coding RNA from single cells (2)
Two-color microarray (1)
Human - High-throughput sequencing (1)
Animal - High-throughput sequencing (1)
Ribo-seq (1)
Methylation profiling by array (1)
RNA-seq of non coding RNA (1)

Release Date

2014 (80)
2013 (78)
2010 (77)
2021 (72)
2015 (70)
2022 (69)
2020 (69)
2016 (67)
2025 (65)
2024 (62)
2017 (62)
2012 (58)
2023 (53)
2018 (53)
2019 (50)
2011 (49)
2009 (41)
2008 (37)
2007 (33)
2026 (22)
2006 (15)
2005 (11)
2001 (8)
2003 (6)
2000 (6)
2002 (5)
1998 (5)
1999 (3)
2004 (2)

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Comparative label-free lipidomic analysis of Mycobacterium tuberculosis during dormancy and reactivation

Mycobacterium tuberculosis employs several strategies to combat and adapt to adverse conditions encountered inside the host. The non-replicative dormant state of the bacterium is linked to drug resistance and slower response to anti-tubercular therapy. It is known that alterations in lipid content a...

2018-10-22 | MTBLS304 | MetaboLights

Generation and characterization of thiol-deficient Mycobacterium tuberculosis mutants

Mycothiol (MSH) and ergothioneine (ERG) are thiols able to compensate for each other to protect mycobacteria such as Mycobacterium smegmatis against oxidative stress. Gamma-glutamylcysteine (GGC), another thiol and an intermediate in ERG biosynthesis has detoxification abilities. Five enzymes are in...

2018-07-05 | MTBLS661 | MetaboLights

Exploiting Vitamin B6 Dependency: BVL3572S Inhibits HisC and AlaA to Kill Mycobacterium tuberculosis

Tuberculosis remains the leading cause of death from a single infectious agent worldwide, and the growing prevalence of multi-drug resistant Mycobacterium tuberculosis (Mtb) underscores the urgent need for antibiotics with novel mechanisms of action. Here, we characterize BVL3572S, a hydroxamic a...

2026-06-23 | MTBLS14782 | MetaboLights

Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis

Gene rv3722c of Mycobacterium tuberculosis is essential for in vitro growth, and encodes a putative pyridoxal phosphate-binding protein of unknown function. Here we use metabolomic, genetic and structural approaches to show that Rv3722c is the primary aspartate aminotransferase of M. tuberculosis...

2020-05-01 | MTBLS1559 | MetaboLights

Activity-Based Metabolic Profiling of M. tuberculosis H37Rv Rv3208

Not available

ORGANISM(S): Mycobacterium tuberculosis H37Rv

ST000937 | MetabolomicsWorkbench

Activity-Based Metabolic Profiling of M. tuberculosis H37Rv Rv1130

Not available

ORGANISM(S): Mycobacterium tuberculosis H37Rv

ST000234 | MetabolomicsWorkbench

Activity-Based Metabolic Profiling of M. tuberculosis H37Rv Rv2247

Not available

ORGANISM(S): Mycobacterium tuberculosis H37Rv