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This project focused in the proteomic characterization of the secreted proteome of a Rv1002c (Protein mannosyltransferase) knock-out mutant and its wild type counterpart. The analysis was carried out using a M. tuberculosis ΔleuDΔpanCD auxotroph Rv1002c wild type compared to M. tuberculosis ΔleuDΔp...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2019-04-09 | PXD011081 | Pride
Mycobacterium tuberculosis strain:2172 Genome sequencing
The study aims at understanding the global nature of the immune responses within the the lung tissue 28 days post infection with Mycobacterium tuberculosis. Comparing the whole transcriptome of infected lungs to that of an uninfected lungs revealed a plethora of immune mechanisms driven by various c...
ORGANISM(S): Mus musculus 
Mycobacterium tuberculosis Genome sequencing and assembly
This study investigates the proteomic alterations in human monocytic cell line (THP1) subsequent to infection with different strains of mycobacterium tuberculosis (H37Ra, H37Rv, BND433 and JAL2287) using the SWATH-MS strategy. THP1 proteome was analysed after 6, 18, 30 and 42 hours of infection with...
ORGANISM(S): Homo sapiens (Human) Mycobacterium tuberculosis 
2021-01-05 | PXD022352 | Pride
Genomics
Mycobaterium tuberculosis H37Rv random insertion mutant pool samples
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