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ORGANISM(S): Homo sapiens 
To experimentally investigate the function of hsa-miR-511-5p in AML monoblasts, we employed miRNA mimic mediated up-regulation of miR-511 in THP1 cells and subsequently analyzed a comprehensive gene expression profile. 4 samples of two independent miRNA mimic experiments were analyzed. THP1 monoblas...
ORGANISM(S): Homo sapiens 
ChIP-seq of Thp1-mono, Thp1-macro, and Thp1-M.tb
ATAC-seq of Thp1-mono, Thp1-macro, and Thp1-M.tb
This study investigates the proteomic alterations in human monocytic cell line (THP1) subsequent to infection with different strains of mycobacterium tuberculosis (H37Ra, H37Rv, BND433 and JAL2287) using the SWATH-MS strategy. THP1 proteome was analysed after 6, 18, 30 and 42 hours of infection with...
ORGANISM(S): Homo sapiens (Human) Mycobacterium tuberculosis 
2021-01-05 | PXD022352 | Pride
We aimed to clarify the cell-free DNA (cfDNA) physiological role. We exposed THP1 cells to plasma from healthy individuals with and without cfDNA and compared their transcriptomes and proteomes.
ORGANISM(S): Homo sapiens 
SP110b is an interferon (IFN)-induced nuclear protein and may function as a transcriptional co-activator/repressor. IFNγ activates monocytes/macrophages thereby mediating inflammation. However, uncontrolled activation induces monocyte/macrophage cell death, which may cause immunopathology. We have d...
ORGANISM(S): Homo sapiens 
THP1 cells were ChIPed with H3K56Ac Comparison of selected chromatin marks in THP1 cells
ORGANISM(S): Homo sapiens 
RNA-seq was performed to identify differences in the transcriptome between wildtype, CDK2-knockdown and JUN-knockdown THP1 cells treated with LPS against untreated controls.
ORGANISM(S): Homo sapiens 
Analysis of mRNA in THP1 (human monocytic leukemia) cell line in order to correlate miRNA activity with target abundance. THP1 mRNA profiles were generated in triplicates by deep-sequencing in Illumina HiSeq2000.
ORGANISM(S): Homo sapiens 
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