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ProteomicsMycofactocin is critical for Mycobacterium tuberculosis adaptation into microaerophilic conditions
Mycofactocin is a new class of peptide-derived redox cofactor whose structural elucidation and functional characterization have recently received enormous focus. Among the six-gene cluster, mftD mediates a probable penultimate step in mycofactocin biosynthesis. MftD is a putative lactate dehydrogena...
ORGANISM(S): Mycobacterium smegmatis 
2021-07-05 | PXD023045 | Pride
Mycobacterium tuberculosis Hypoxia Mycofactocin Redox regulationamyloid formation Redox regulation Lactate metabolism 
GenomicsMftG is crucial for alcohol metabolism of mycobacteria by linking mycofactocin oxidation to respiration
MftG is crucial for alcohol metabolism of mycobacteria by linking mycofactocin oxidation to respiration
PRJNA1053775 | ENA
TranscriptomicsMftG is crucial for alcohol metabolism of mycobacteria by linking mycofactocin oxidation to respiration
Mycofactocin is a redox cofactor essential for the alcohol metabolism of Mycobacteria. While the biosynthesis of mycofactocin is well established, the mftG gene, which encodes an oxidoreductase of the glucose-methanol-choline superfamily remained functionally uncharacterized. Here, we show that MftG...
ORGANISM(S): Mycolicibacterium smegmatis MC2 155 
2024-03-01 | GSE250373 | GEO
GenomicsMycofactocin is associated with ethanol metabolism in Mycobacteria
Mycofactocin is associated with ethanol metabolism in Mycobacteria
PRJNA497261 | ENA
UnknownMftG is crucial for ethanol metabolism of mycobacteria by linking mycofactocin oxidation to respiration.
Not available
S-EPMC11778925 | biostudies-literature
GenomicsThe catabolism of ethylene glycol by Rhodococcus jostii RHA1 and its dependence on mycofactocin
The catabolism of ethylene glycol by Rhodococcus jostii RHA1 and its dependence on mycofactocin
PRJNA1086512 | ENA
UnknownMechanistic elucidation of the mycofactocin-biosynthetic radical S-adenosylmethionine protein, MftC.
Not available
S-EPMC5546040 | biostudies-literature
UnknownS-Adenosylmethionine (SAM)-Dependent Methyltransferase MftM is Responsible for Methylation of the Redox Cofactor Mycofactocin.
Not available
S-EPMC9679996 | biostudies-literature
UnknownSpectroscopic and Electrochemical Characterization of the Mycofactocin Biosynthetic Protein, MftC, Provides Insight into Its Redox Flipping Mechanism.
Not available
S-EPMC6380935 | biostudies-literature
TranscriptomicsThe catabolism of ethylene glycol by Rhodococcus jostii RHA1 and its dependence on mycofactocin
Ethylene glycol (EG) is a widely used industrial chemical with manifold applications and is also generated in the degradation of plastics such as PET. Rhodococcus jostii RHA1 (RHA1), a potential biocatalytic chassis, grows on EG. Transcriptomic analyses revealed four clusters of genes potentially in...
ORGANISM(S): Rhodococcus jostii 
2024-03-15 | GSE261336 | GEO
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