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ProteomicsMYCT1 CONTROLS ENVIRONMENTAL SENSING IN HUMAN HEMATOPOIETIC STEM CELLS
Hematopoietic stem cells (HSC) rely on a unique regulatory machinery that facilitates life-long blood production and enables reconstitution of the entire hematopoietic system upon transplantation. However, the biological processes governing human HSC self-renewal and engraftment ability are poorly u...
ORGANISM(S): Homo sapiens (Human) 
2024-04-15 | PXD042257 | Pride
Myct1 Proteomics Stem cells 
UnknownMYCT1-TV, a novel MYCT1 transcript, is regulated by c-Myc and may participate in laryngeal carcinogenesis.
Not available
S-EPMC3187795 | biostudies-literature
GenomicsMYCT1 Controls Environmental Sensing in human Hematopoietic Stem Cells [scRNA-seq]
MYCT1 Controls Environmental Sensing in human Hematopoietic Stem Cells [scRNA-seq]
PRJNA971733 | ENA
GenomicsMYCT1 Controls Environmental Sensing in human Hematopoietic Stem Cells [RNA-seq]
MYCT1 Controls Environmental Sensing in human Hematopoietic Stem Cells [RNA-seq]
PRJNA971732 | ENA
GenomicsMYCT1 Controls Environmental Sensing in human Hematopoietic Stem Cells [scRNA-seq Dextran]
MYCT1 Controls Environmental Sensing in human Hematopoietic Stem Cells [scRNA-seq Dextran]
PRJNA1072098 | ENA
TranscriptomicsMYCT1 Controls Environmental Sensing in human Hematopoietic Stem Cells [scRNA-seq]
We identified a novel HSC regulatory gene, MYCT1 (MYC target 1), that is selectively expressed in undifferentiated human HSPC and is critical for human HSC expansion and engraftment. MYCT1 knockdown (KD) in human fetal liver and cord blood (CB) HSPCs impaired expansion ex vivo and engraftment after ...
ORGANISM(S): Homo sapiens 
2024-04-08 | GSE232361 | GEO
GenomicsNext Generation Sequencing Facilitates Quantitative Analysis of Transcriptomes at LncRNA and mRNA and miRNA levels between Hep2 cells with stable transfection of MYCT1 and non-transfection of MYCT1
Next Generation Sequencing Facilitates Quantitative Analysis of Transcriptomes at LncRNA and mRNA and miRNA levels between Hep2 cells with stable transfection of MYCT1 and non-transfection of MYCT1
PRJNA507997 | ENA
UnknownMYCT1 attenuates renal fibrosis and tubular injury in diabetic kidney disease.
Not available
S-EPMC10470386 | biostudies-literature
TranscriptomicsMYCT1 Controls Environmental Sensing in human Hematopoietic Stem Cells [scRNA-seq Dextran]
We identified a novel HSC regulatory gene, MYCT1 (MYC target 1), that is selectively expressed in undifferentiated human HSPC and is critical for human HSC expansion and engraftment. MYCT1 knockdown (KD) in human fetal liver and cord blood (CB) HSPCs impaired expansion ex vivo and engraftment after ...
ORGANISM(S): Homo sapiens 
2024-04-08 | GSE254857 | GEO
UnknownMYCT1 inhibits hematopoiesis in diffuse large B-cell lymphoma by suppressing RUNX1 transcription.
Not available
S-EPMC10763471 | biostudies-literature
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