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ProteomicsIschemic preconditioning predominantly affects phosphosites involved in myocardial contraction and promotes myocardial stunning while reducing infarction size in rats.
Background: Ischemic preconditioning (IPC), i.e., brief periods of ischemia, protect the heart from subsequent prolonged ischemic injury, and reduces infarction size. Myocardial stunning refers to transient loss of contractility in the heart after myocardial ischemia that recovers without causing pe...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-05-15 | PXD050441 | Pride
Myocardial infarction Phosphoproteomics Ischemic preconditioning Echocardiography Speckle tracking analysis Myocardial stunning 
UnknownIschemic preconditioning affects phosphosites and accentuates myocardial stunning while reducing infarction size in rats.
Not available
S-EPMC10978780 | biostudies-literature
ProteomicsComparison of the proteomic landscape in experimental ischemia-reperfusion with versus without ischemic preconditioning
Myocardial ischemic preconditioning (IPC) enhances myocardial resilience to ischemic injury. Myocardial stunning is a transient, reversible dysfunction, while necrosis involves irreversible cell death. The relationship between IPC, stunning, and necrosis is not well understood, requiring further mol...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-04-09 | PXD050310 | Pride
Ischemia-reperfusion injury  tissue remodeling  therapeutic targets Myocardial ischemic preconditioning: myocardial stunning  myocardial infarction  cardiac proteomics  temporal changes 
UnknownEffect of intradialytic exercise training on hemodialysis-induced myocardial stunning: a pilot-controlled trial.
Not available
S-EPMC11852286 | biostudies-literature
UnknownMyocardial stunning secondary to erroneous administration of intravenous epinephrine.
Not available
S-EPMC10026126 | biostudies-literature
UnknownATP-Sensitive Potassium Channel Opener Diazoxide Reduces Myocardial Stunning in a Porcine Regional With Subsequent Global Ischemia Model.
Not available
S-EPMC9851454 | biostudies-literature
GenomicsIschaemic preconditioning blunted myocardial DNA methylation and regulated myocardial transcriptome in ischaemic reperfusion settings
Ischaemic preconditioning blunted myocardial DNA methylation and regulated myocardial transcriptome in ischaemic reperfusion settings
PRJNA1199904 | ENA
UnknownGinsenoside Rb1 Improves Post-Cardiac Arrest Myocardial Stunning and Cerebral Outcomes by Regulating the Keap1/Nrf2 Pathway
Not available
S-EPMC10003120 | biostudies-literature
UnknownCardiac stunning during haemodialysis: the therapeutic effect of intra-dialytic exercise.
Not available
S-EPMC8087145 | biostudies-literature
TranscriptomicsIschaemic preconditioning blunted myocardial DNA methylation and regulated myocardial transcriptome in ischaemic reperfusion settings
Background. Ischemic preconditioning (IPC) reduces infarct size but may increase the extent of reversible cardiac dysfunction (myocardial stunning). DNA methylation is thought to regulate IPC-induced gene expression, impacting inflammation, oxidative stress, apoptosis, and DNA repair pathways. Aims....
ORGANISM(S): Rattus norvegicus 
2025-12-02 | GSE284606 | GEO
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