Sort   by:  
 Page size 
TranscriptomicsMyocilin regulates cell proliferation and survival by activating the ERK pathway
Myocilin, a causative gene for open-angle glaucoma, encodes a secreted glycoprotein of unknown function. To elucidate its function(s), we produced a stably transfected HEK293 cell line expressing myocilin and compared the expression profiles between the myocilin-expressing cell line and a vector con...
ORGANISM(S): Homo sapiens 
2014-05-21 | E-GEOD-53985 | biostudies-arrayexpress
TranscriptomicsMyocilin effect on retina. Russell-7U24NS043571-02
Glaucoma is a neurodegenerative disease in which vision is lost as a result of the apoptosis of retinal ganglion cells. When the trabecular meshwork cells, that regulate aqueous humor outflow, are stressed as they are in some forms of glaucoma, they considerably up-regulated secretion of a protein c...
ORGANISM(S): Mus musculus 
2004-10-14 | GSE1835 | GEO
TranscriptomicsMyocilin regulates cell proliferation and survival by activating the ERK pathway
Myocilin, a causative gene for open-angle glaucoma, encodes a secreted glycoprotein of unknown function. To elucidate its function(s), we produced a stably transfected HEK293 cell line expressing myocilin and compared the expression profiles between the myocilin-expressing cell line and a vector con...
ORGANISM(S): Homo sapiens 
2014-05-21 | GSE53985 | GEO
Proteomicshydrogen deuterium uptake comparison between wild-type, I499F, and D380A variants of the myocilin olfactomedin domain
Studies of folded-to-misfolded transitions using model protein systems reveal a range of unfolding needed for exposure of amyloid-prone regions for subsequent fibrillization. Here, we probe the relationship between unfolding and aggregation for glaucoma-associated myocilin. Mutations within the olfa...
ORGANISM(S): Homo sapiens (Human) 
2023-11-27 | PXD045520 | Pride
Dynamics Glaucoma Myocilin 
TranscriptomicsMYOC.WTvsNull
Comparison of human trabecular meshwork transcriptomes of cells overexpressing wild-type Myocilin
ORGANISM(S): Homo sapiens 
2012-10-06 | E-MEXP-3440 | biostudies-arrayexpress
UnknownCharacterization of rabbit myocilin: Implications for human myocilin glycosylation and signal peptide usage.
Not available
S-EPMC156599 | biostudies-literature
TranscriptomicsTranscription profiling of mouse retina response to myocilin. Russell-7U24NS043571-02
Glaucoma is a neurodegenerative disease in which vision is lost as a result of the apoptosis of retinal ganglion cells. When the trabecular meshwork cells, that regulate aqueous humor outflow, are stressed as they are in some forms of glaucoma, they considerably up-regulated secretion of a protein ...
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-1835 | biostudies-arrayexpress
GenomicsMus musculus
Myocilin effect on retina. Russell-7U24NS043571-02
PRJNA90559 | ENA
UnknownMyocilin Regulates Metalloprotease 2 Activity Through Interaction With TIMP3.
Not available
S-EPMC5644706 | biostudies-literature
UnknownMolecular architecture and modifications of full-length myocilin.
Not available
S-EPMC8511078 | biostudies-literature
Sort   by:  
 Page size