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TranscriptomicsTranscription profiling of mouse skeletal muscle gene expression after myostatin knockout in mature animals
RNA from 5 mice with postdevelopmental knockout of myostatin and 5 mice with normal myostatin expression was analyzed with comprehensive oligonucleotide microarrays. Myostatin depletion affected the expression of several hundred genes at nominal P < 0.01, but fewer than a hundred effects were statis...
ORGANISM(S): Mus musculus 
2009-03-28 | E-GEOD-15349 | biostudies-arrayexpress
TranscriptomicsDifferential miroRNA expression in myostatin knockout mice
To identify microRNAs involved in myostatin-deficient muscular hypertrophy, we compared miRNA expression in wild-type and myostatin knockout mice. Total RNA, isolated from three wild-type or myostatin knockout mice, was pooled and then used for microarray analysis.
ORGANISM(S): Mus musculus 
2013-12-17 | E-GEOD-49523 | biostudies-arrayexpress
GenomicsDifferential miroRNA expression in myostatin knockout mice
To identify microRNAs involved in myostatin-deficient muscular hypertrophy, we compared miRNA expression in wild-type and myostatin knockout mice.
ORGANISM(S): Mus musculus 
2013-12-17 | GSE49523 | GEO
ProteomicsMyostatin Deficiency But Not Anti-Myostatin Blockade Induces Marked Proteomic Changes in Mouse Skeletal Muscle
Recent studies have reported the deleterious physiological and metabolic changes in Mstn-/- mice including impaired force generation and susceptibility to contraction-induced injury. Such observations have raised the concerns about the functional quality of the increased muscle resulting from thera...
ORGANISM(S): Mus musculus (Mouse) 
2016-05-31 | PXD003747 | Pride
Myostatin knockout Silac mouse Gastrocnemius Quantitative proteomics Anti-myostatin blocking antibody 
TranscriptomicsSkeletal muscle gene expression after myostatin knockout in mature mice
RNA from 5 mice with postdevelopmental knockout of myostatin and 5 mice with normal myostatin expression was analyzed with comprehensive oligonucleotide microarrays. Myostatin depletion affected the expression of several hundred genes at nominal P < 0.01, but fewer than a hundred effects were statis...
ORGANISM(S): Mus musculus 
2009-03-24 | GSE15349 | GEO
UnknownSkeletal muscle gene expression after myostatin knockout in mature mice.
Not available
S-EPMC3774565 | biostudies-literature
GenomicsMus musculus
Differential miroRNA expression in myostatin knockout mice
PRJNA214101 | ENA
GenomicsMus musculus
Skeletal muscle gene expression after myostatin knockout in mature mice
PRJNA116581 | ENA
UnknownMyostatin gene knockout mediated by Cas9-D10A nickase in chicken DF1 cells without off-target effect.
Not available
S-EPMC5411835 | biostudies-literature
UnknownGeneration of myostatin B knockout yellow catfish (Tachysurus fulvidraco) using transcription activator-like effector nucleases.
Not available
S-EPMC4050710 | biostudies-literature
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