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MetabolomicsDeciphering the Role of N-Acetyltransferase 10 in Thalamic Hemorrhage Through Integrative Multi-Omics and Experimental Validation

Thalamic hemorrhage (TH) is a severe neurological condition, the molecular mechanisms of which are poorly understood, particularly in clinical settings. N-acetyltransferase 10 (NAT10), a regulator of RNA N4-acetylcytidine (ac4C) modification, has been implicated in cell cycle regulation and ident...

2025-11-18 | MTBLS11752 | MetaboLights
ProteomicsStructural, molecular and cellular impact of the Ogden syndrome mutant N-terminal acetyltransferase hNaa10-Ser37Pro
Abstract still has to be written. The obtained peptide mixtures were introduced into an LC-MS/MS system, the Ultimate 3000 (Dionex, Amsterdam, The Netherlands) in-line connected to an LTQ Orbitrap XL mass spectrometer (Thermo Fisher Scientific, Bremen, Germany). Samples were first loaded on a trapp...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-03-13 | MSV000083564 | MassIVE
MetabolomicsGNPS - Self-Resistance Mechanism mediated by N-acetyltransferase PamZ
Self-resistance mechanism mediated by N-acetyltransferase PamZ by deactivation of own antibacterial agent paenilamicin in Paenibacillus larvae, the causative agent of the honey bee disease American Foulbrood.
ORGANISM(S): Paenibacillus Larvae Subsp. Larvae 04-309 (ncbitaxon:697284) 
2022-01-18 | MSV000088695 | GNPS
ProteomicsGlobal profiling of acetylation reveals a new family with dual-specific lysine and N-terminal acetyltransferase activity in the plastids of Arabidopsis
Protein acetylation is a universally conserved modification occurring on N-termini (N--acetylation, NTA) and on internal lysines residues (-lysine-acetylation, KA). So far, NTA and KA were known to be supported by distinct families of enzymes (NATs and KATs, respectively), despite most of them sha...
ORGANISM(S): Escherichia Coli 
2020-07-07 | PXD015875 | JPOST Repository
TranscriptomicssiRNA knockdown of NatB N-terminal acetyltransferase (hNAT5) expression in human Hela cells with specific siRNAs
Search for genes differently expressed when we inhibit NatB N-terminal acetyltransferase. We compare gene expression after inhibiting hNAT5 expression in Hela cells with specific siRNAs expressed with adenoviruses. Experiment Overall Design: We analyzed duplicate samples and we used as controls Hela...
ORGANISM(S): Homo sapiens 
2008-04-05 | E-GEOD-10779 | biostudies-arrayexpress
GenomicsHistone N-terminal acetyltransferase NAA40 links one-carbon metabolism to chemoresistance
Histone N-terminal acetyltransferase NAA40 links one-carbon metabolism to chemoresistance
PRJNA704699 | ENA
ProteomicsKnock out of NAA50 in A. thaliana
Knockout of the N-acetyltransferase AtNAA50 causes severe dwarfism the model plant Arabidopsis thaliana but does not affect the activity of the essential NatA complex.
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2020-05-27 | PXD017663 | JPOST Repository
Genomics
Aminoglycoside N-acetyltransferase sequencing
PRJNA360018 | ENA
TranscriptomicsNatB N-terminal acetyltransferase (hNAT5) inhibition
Search for genes differently expressed when we inhibit NatB N-terminal acetyltransferase. We compare gene expression after inhibiting hNAT5 expression in Hela cells with specific siRNAs expressed with adenoviruses. Keywords: gene expression comparison
ORGANISM(S): Homo sapiens 
2008-03-12 | GSE10779 | GEO
GenomicsN-acetyltransferase NAT10 Controls Cell Fates via RNA Cytidine Acetylation
N-acetyltransferase NAT10 Controls Cell Fates via RNA Cytidine Acetylation
PRJNA865915 | ENA
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