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Genomic analysis has revealed the existence of a large number of long non-coding RNAs (lncRNAs) in a variety of organisms, including yeast. lncRNAs might have several biological functions during normal cell growth and development. Cells are subject to dramatic changes of gene expression in response ...
ORGANISM(S): Saccharomyces cerevisiae 
Cells are subjected to dramatic changes on gene expression upon environmental changes. Stress causes a general down-regulation of gene expression together with the induction of a set of stress-responsive genes. Genome wide localisation studies showed major changes on Pol II localisation towards stre...
ORGANISM(S): Saccharomyces cerevisiae 
Cellular heterogeneity is a key determinant for disease outcome and therapeutic treatments across virtually all organisms. Variability within a population underlies the different cellular responses that ultimately determine cell fate and phenotypic diversity. Little is known about the molecular basi...
ORGANISM(S): Saccharomyces cerevisiae 
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