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MetabolomicsMultiomics of tomato glandular trichomes reveals distinct features of central carbon metabolism supporting high productivity of specialized metabolites
Glandular trichomes are metabolic cell factories with the capacity to produce large quantities of secondary metabolites. Little is known about the connection between central carbon metabolism and metabolic productivity for secondary metabolites in glandular trichomes. To address this gap in our know...
2017-04-25 | MTBLS297 | MetaboLights
TranscriptomicsExpression profiling, Lin-9 depletion array in D3 mES cells
Lin-9 was depleted in ES-D3 cells (ATCC CRL-1934) and the resulting expression profile changes mapped via microarrays
ORGANISM(S): Mus musculus 
2013-05-13 | E-MTAB-1490 | biostudies-arrayexpress
TranscriptomicsAntibody-based selective isolation of atrial and ventricular cardiomyocytes by differential expression of integrin α6 (CD49f)
Central questions like cardiomyocyte subtype emergence during cardiogenesis or availability of cardiomyocyte subtypes for cell replacement therapy require selective identification and purification of atrial and ventricular cardiomyocytes. However, characterization and implementation of pure cardiomy...
ORGANISM(S): Mus musculus 
2015-12-14 | E-GEOD-57131 | biostudies-arrayexpress
MetabolomicsMonocolonization with Bacteroides thetaiotaomicron exerts region-specific effects on Alzheimer’s disease-related traits in the murine brain

Bacteroides thetaiotaomicron (B. theta) dominates the gut microbiome of most mammals. This strictly anaerobic gut symbiont colonizes the mucus layer of host intestinal epithelial cells in both healthy and diseased conditions. Reduced neuronal and vagal afferent innervation observed in ge...

2025-12-15 | MTBLS12896 | MetaboLights
TranscriptomicsThe composition and function of chaperone networks in Solanum lycopersicum explored by transcriptome sequencing and microarray meta-analysis
Heat shock proteins (Hsps) are molecular chaperones primarily involved in maintenance of protein homeostasis. Their function has been best characterized in heat stress (HS) response during which Hsps are transcriptionally controlled by heat stress transcription factors (Hsfs). The role of Hsfs and H...
ORGANISM(S): Solanum lycopersicum 
2014-08-01 | E-GEOD-56611 | biostudies-arrayexpress
TranscriptomicsExpression of orthologs of ribosome biogenesis factors in vegetative and reproductive tissues in Solanum lycopersicum
Ribosome biogenesis is a major cellular processes involving a large inventory of proteinaceous and RNA cofactors. Recent bioinformatics approaches discovered a large but not complete overlap of the inventory between yeast, mammals and plants. We re-inspected the complexity of ribosome biogenesis fac...
ORGANISM(S): Solanum lycopersicum 
2014-08-01 | E-GEOD-56610 | biostudies-arrayexpress
TranscriptomicsIntrinsic regenerative potential of murine cochlear supporting cells
P3 Math1-nGFP mouse cochlear sensory epithelia, consisting of greater and lesser epithelial ridges (GER & LER) including the organ of Corti with nGFP-positive hair cells, were dissected, dissociated into single cells, and labeled with propidium iodide and three CD marker antibodies. The cell suspen...
ORGANISM(S): Mus musculus 
2014-10-22 | E-GEOD-62582 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of nine European maize (Zea mays L.) inbred lines and nine corresponding hybrids
In this study expression levels of 732 genes were analyzed for European maize (Zea mays L.) inbred lines (4 Flint and 5 Dent) and nine corresponding hybrids by microarray analysis. The selection of the 732 genes was based on a previous study (Thiemann et al., Theor Appl Genet 2010, 120:401-413), whi...
ORGANISM(S): Zea mays 
2014-04-03 | E-GEOD-52411 | biostudies-arrayexpress
TranscriptomicsSca-1 expression defines different developmental stages of mouse PDC that show functional heterogeneity in the endosomal but not lysosomal TLR9 response
Plasmacytoid dendritic cells (PDC) play an important role in innate and adaptive immunity and were shown to be identical to previously described natural IFN-M-NM-1-producing cells (NIP). Here, we describe two functionally distinct PDC subpopulations that are characterized by the differential express...
ORGANISM(S): Mus musculus 
2013-12-21 | E-GEOD-42860 | biostudies-arrayexpress
TranscriptomicsRAI2 overexpression in MDA-MB231
MDA-MB231 cells were transfected with control vector, RAI2-overexpression vector, or vector with RAI2-4A, which has a mutated interaction domain w.r.t. CtBP/CtBP2 Three replicates each of control condition, RAI2 overexpression or RAI2-4A overexpression.
ORGANISM(S): Homo sapiens 
2015-06-15 | E-GEOD-65489 | biostudies-arrayexpress
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