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Naja melanoleuca
Three main top-down mass spectrometry methodologies were employed in a proof-of-concept study to characterise selected three finger toxins and phospholipase A2 toxins from the forest cobra (Naja melanoleuca) venom. The novel utility of data-independent acquisition, alternative hybrid ECD-CID fragmen...
ORGANISM(S): Naja melanoleuca 
2024-09-05 | PXD052561 | Pride
Comprehensive understanding of venom compositions and in-depth characterisation of the various proteoforms are necessary to aid the development of targeted antivenom strategies. This work utilises an integrated 'omics' and intact mass spectrometry-based approach to profile the diversity within the v...
ORGANISM(S): Naja melanoleuca 
2024-01-03 | PXD045209 | Pride
African forest cobra venom is a rich source of bioactive compounds such as cytotoxins, which cause tissue necrosis and descending paralysis. However, the venom has also been identified as a potential source of therapeutic agents, including anticancer agents. In this study, we evaluate the anticance...
ORGANISM(S): Cellular Organisms 
Venomous snakes are important parts of the ecosystem, and their behavior and evolution have been shaped by their surrounding environments over the eons. This is reflected in their venoms, which are typically highly adapted for their biological niche, including their diet and defense mechanisms for d...
ORGANISM(S): Bitis gabonica Naja nivea Naja annulifera Naja anchietae Naja katiensis Dendroaspis polylepis Echis pyramidum Bitis arietans Naja nigricincta Cerastes cerastes Dendroaspis angusticeps (Eastern green mamba) (Naja angusticeps) Bitis rhinoceros Naja pallida Naja ashei Echis leucogaster Echis ocellatus Dendroaspis viridis Naja senegalensis Bitis nasicornis Dendroaspis jamesoni Naja nubiae Hemachatus haemachatus Naja mossambica Naja haje Naja nigricollis Naja melanoleuca 
2022-10-17 | PXD036161 | Pride
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