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TranscriptomicsGene expression signatures in miR-29c overexpressed gastric cancer cells.
To explain the mechanism that miR-29c affects the cell proliferation, we attempted to identify the miR-29c target genes in gastric carcinoma. The expression profiles in MKN45, MKN7 and MKN74 cells transfected with miR-29c oligo or Negative control oligo were obtained from microarray analysis. Then, ...
ORGANISM(S): Homo sapiens 
2013-03-27 | E-GEOD-38581 | biostudies-arrayexpress
TranscriptomicsGenomic profiling of primary and metastatic clear cell renal cell carcinoma by array-based comparative genomic hybridization.
In this study, we investigated CNAs of 20 primary clear cell renal cell caricinomas (ccRCCs), 20 corresponding metastases and another subsets of 30 primary ccRCCs by 44k oligonucleotide-based array comparative genomic hybridization (array CGH). 20 primary ccRCCs, 20 corresponding metastases and anot...
ORGANISM(S): Homo sapiens 
2014-10-16 | E-GEOD-43477 | biostudies-arrayexpress
TranscriptomicsGenomic profiling of 19 renal cell carcinoma samples from patients with end-stage renal disease
In this study, 19 tumor samples from patients with renal cell carcinoma (RCC)-end-stage renal disease (ESRD) were analyzed by array comparative genomic hybridization (array CGH) using the Agilent Whole Human Genome 4× Array. 19 cystic disease samples from patients with RCC-ESRD
ORGANISM(S): Homo sapiens 
2012-04-01 | E-GEOD-33117 | biostudies-arrayexpress
TranscriptomicsGenomic profiling of gastric adenomas by array-based comparative genomic hybridization
In this study, we investigated CNAs of 20 gastric CIS (Vienna category 4.2) and 20 adenomas, including 7 low-grade adenomas (LGA; Vienna category 3) and 13 high-grade adenomas (HGA; Vienna category 4.1), by 244k oligonucleotide-based array comparative genomic hybridization (array CGH). 20 gastric ad...
ORGANISM(S): Homo sapiens 
2010-06-18 | E-GEOD-19574 | biostudies-arrayexpress
TranscriptomicsGenomic profiling of oral squamous cell carcinoma by array-based comparative genomic hybridization
In this study, we investigated CNAs of 40 tumor samples from 25 patients, including 15 metastatic primary tumor (MPT), paired neck lymph-node metastasis (LNM) and 10 non-metastatic primary tumor (NMPT), by 44k oligonucleotide-based array comparative genomic hybridization (array CGH). 15 MPT vs 15 LN...
ORGANISM(S): Homo sapiens 
2013-09-08 | E-GEOD-36942 | biostudies-arrayexpress
TranscriptomicsDownregulation of WDR20 due to loss of 14q is involved in the malignant transformation of clear cell renal cell carcinoma
Previously, we have reported that genomic loss of 14q occurs more frequently in high grade clear cell renal cell carcinomas (ccRCCs) than low grade ones and shows a significant impact on the expression levels of genes located on this region, suggesting that the genes located on the region and downre...
ORGANISM(S): Homo sapiens 
2016-08-09 | E-GEOD-71963 | biostudies-arrayexpress
TranscriptomicsGenomic copy number aberrations of 11 gastric cancer cell lines
Genomic copy number aberrations of 11 gastric cancer cell lines were analyzed by 244k CGH array from Agilent Technologies. Based on this results, we separated the 11 cell lines into 2 groups, with and without copy number increase at chromosome 20q13 We performed array comparative genomic hybridizati...
ORGANISM(S): Homo sapiens 
2016-04-01 | E-GEOD-67604 | biostudies-arrayexpress
TranscriptomicsIntratumoral genomic heterogeneity in submucosal-invasive gastric cancer
In this study, we investigated CNAs of 59 tumor samples from 27 patients with submucosal-invasive gastric cancers (SMGC) by 44k oligonucleotide-based array comparative genomic hybridization (array CGH). 23 mucosal portion of SMGC vs 23 paired submucosal (SM) portion of SMGC, 9 SM portion vs 9 paired...
ORGANISM(S): Homo sapiens 
2012-01-20 | E-GEOD-26800 | biostudies-arrayexpress
TranscriptomicsGenomic profiling of renal cell carcinoma in patients with end-stage renal disease
In this study, eighty tumor samples from 63 patients with renal cell carcinoma (RCC)-end-stage renal disease (ESRD) were analyzed by array comparative genomic hybridization (array CGH) using the Agilent Whole Human Genome 4×44K Oligo Micro Array. 79 tumor samples from 63 patients with RCC-ESRD
ORGANISM(S): Homo sapiens 
2012-03-24 | E-GEOD-28601 | biostudies-arrayexpress
TranscriptomicsGenomic profiling of gastric carcinoma in situ by array-based comparative genomic hybridization
In this study, we investigated CNAs of 20 gastric CIS (Vienna category 4.2) and 20 adenomas, including 7 low-grade adenomas (LGA; Vienna category 3) and 13 high-grade adenomas (HGA; Vienna category 4.1), by 244k oligonucleotide-based array comparative genomic hybridization (array CGH). 20 gastric ca...
ORGANISM(S): Homo sapiens 
2010-01-31 | E-GEOD-19566 | biostudies-arrayexpress
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