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UnknownUp-regulation of phospholipid hydroperoxide glutathione peroxidase in rat casein-induced polymorphonuclear neutrophils.
Antioxidant enzymes play key roles in the protection of cells from oxidative damage. Little is known, however, about the expression of antioxidants and/or their roles in PMNs (polymorphonuclear leucocytes), which are thought to suffer from oxidative stress in an inflammation site. In the present pap...
S-EPMC1175104 | biostudies-literature
UnknownEffects of a golfers' low back pain exercise prevention program on physical function and golf performance in adolescent golfers: a double-blind, randomized, sham-controlled trial.

Purpose

Injury prevention programs for adolescent athletes include pre-game exercise programs designed to improve individuals physical function. This study aimed to determine the impact of Golfers' Low back pain Exercise prevention Program (GLEP) on physical function and golf performance.
S-EPMC12639999 | biostudies-literature
UnknownWarm-Up Program for Adolescent Golfers Reduces Low Back Pain: A Double-Blind, Randomized Controlled Trial.
Introduction: Low back pain (LBP) is common in golfers. While numerous injury prevention programs exist for youth athletes, there is a significant lack of such programs to prevent LBP in adolescent golfers. Objective: To ascertain the impact of an LBP prevention program on the incidenc...
S-EPMC12358233 | biostudies-literature
UnknownHybrid-argon plasma coagulation for superficial esophageal cancer at risk of airway obstruction: a case report.
Not available
S-EPMC12904748 | biostudies-literature
UnknownStructural basis for the development of SARS 3CL protease inhibitors from a peptide mimic to an aza-decaline scaffold.
Design of inhibitors against severe acute respiratory syndrome (SARS) chymotrypsin-like protease (3CL(pro) ) is a potentially important approach to fight against SARS. We have developed several synthetic inhibitors by structure-based drug design. In this report, we reveal two crystal structures of S...
S-EPMC7159131 | biostudies-literature
UnknownFused-ring structure of decahydroisoquinolin as a novel scaffold for SARS 3CL protease inhibitors.
The design and evaluation of a novel decahydroisoquinolin scaffold as an inhibitor for severe acute respiratory syndrome (SARS) chymotrypsin-like protease (3CL(pro)) are described. Focusing on hydrophobic interactions at the S2 site, the decahydroisoquinolin scaffold was designed by connecting the P...
S-EPMC7111320 | biostudies-literature
UnknownMultiple nutritional and gut microbial factors associated with allergic rhinitis: the Hitachi Health Study.
Several studies suggest the involvement of dietary habits and gut microbiome in allergic diseases. However, little is known about the nutritional and gut microbial factors associated with the risk of allergic rhinitis (AR). We recruited 186 participants with symptoms of AR and 106 control subjects w...
S-EPMC8888718 | biostudies-literature
UnknownThe Autism-Related Protein SETD5 Controls Neural Cell Proliferation through Epigenetic Regulation of rDNA Expression.
Haploinsufficiency of SETD5 is implicated in syndromic autism spectrum disorder (ASD), but the molecular mechanism underlying the pathological role of this protein has remained unclear. We have now shown that Setd5+/- mice manifest ASD-related behavioral phenotypes and that the expression...
S-EPMC7160574 | biostudies-literature
UnknownClinical usefulness of 2-hydroxyglutarate as a biomarker in IDH-mutant chondrosarcoma.

Background

Chondrosarcoma is a common form of malignant bone tumor with limited treatment options. Approximately half of chondrosarcomas harbor gain-of-function mutations in isocitrate dehydrogenase (IDH), and mutant IDH produces 2-hydroxyglutarate (2-HG), which is an oncometabolite that con...
S-EPMC9048072 | biostudies-literature
UnknownCorneal lymphangiogenesis ameliorates corneal inflammation and edema in late stage of bacterial keratitis.
Lymphatic vessels play a crucial role in systemic immune response and regulation of tissue fluid homeostasis. Corneal lymphangiogenesis in bacterial keratitis has not been studied. In this study, we investigated the mechanism and the role of corneal lymphangiogenesis in a murine bacterial keratitis ...
S-EPMC6393676 | biostudies-literature
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