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TranscriptomicsWhole genome gene expression profiling in Adult T-cell Leukemia (ATL) cells and in Normal CD4+ T-cells
HTLV-1 infected individuals stay as carriers for their lifetimes, while the rest of 5% are killed by ATL. ATL leukemogenesis is a complex process involving accumulation of multiple genetic abnormalities in HTLV-1 infected cells. To clarify genetic events underlying ATL leukemogenesis, we conducted c...
ORGANISM(S): Homo sapiens 
2012-02-23 | E-GEOD-33615 | biostudies-arrayexpress
TranscriptomicsComparison of expression profiles of Foxp3(+)epigenetics(-) T cells, Foxp3(-)epigenetics(+) T cells, and Foxp3(+)epigenetics(+) T cells
Analysis of Foxp3(+)epigenetics(-) T cells, Foxp3(-)epigenetics(+) T cells, and Foxp3(+)epigenetics(+) T cells. Results indicate regulatory T cell (Treg) ontogenesis requires two independent processes, expression of the transcription factor Foxp3 and establishment of Treg epigenetic programs induced...
ORGANISM(S): Mus musculus 
2012-11-05 | E-GEOD-25252 | biostudies-arrayexpress
TranscriptomicsWhole genome gene expression profiling in CD4+ T-cells, FACS-sorted based on CADM1/CD7 expression levels, in Adult T-cell Leukemia-lymphoma (ATL) patients, HTLV-1 carriers, and in healthy volunteers.
CADM1 overexpresion and stepwise downregulation of CD7 in CD4+T-cells from ATL patients and HTLV-1 carriers accurately reflect the process of disease, i.e., oligoclonally and clonally exanding cells are accumulated in D (CADM1posCD7dim) and N (CADM1posCD7neg) populations, respectively. Moreover, gen...
ORGANISM(S): Homo sapiens 
2014-06-02 | E-GEOD-55851 | biostudies-arrayexpress
TranscriptomicsmiRNA expression profiling in Adult T-cell Leukemia (ATL) cells and in Normal CD4+ T-cells
HTLV-1 infected individuals stay as carriers for their lifetimes, while the rest of 5% are killed by ATL. ATL leukemogenesis is a complex process involving accumulation of multiple genetic abnormalities in HTLV-1 infected cells. To clarify genetic events underlying ATL leukemogenesis, we conducted c...
ORGANISM(S): Homo sapiens 
2012-02-23 | E-GEOD-31629 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for acute T-cell leukemia/lymphoma (ATL)
SNP array analysis was performed using 168 ATL specimens. To obtain genotypes and intensities for each SNP, Affymetrix 250K SNP arrays were performed for 168 ATL samples.
ORGANISM(S): Homo sapiens 
2012-02-23 | E-GEOD-33602 | biostudies-arrayexpress
UnknownThe complete chloroplast genome sequences of Trapa acornis Nakano (Lythraceae).
Not available
S-EPMC8667907 | biostudies-literature
UnknownTumor-infiltrating CD62L+PD-1-CD8 T cells retain proliferative potential via Bcl6 expression and replenish effector T cells within the tumor.
Not available
S-EPMC7449457 | biostudies-literature
TranscriptomicsGene expression of distinct lung dendritic cell subsets
Pulmonary dendritic cells are heterogenous cells comprise four distinct subsets including two conventional dendritic cell subsets, CD103+ and CD11bhiCD14lo cells, and two monocyte-derived dendritic cell subsets. Their functions in terms of migration and T cell activation are distinct, but genes regu...
ORGANISM(S): Mus musculus 
2015-04-02 | E-GEOD-64896 | biostudies-arrayexpress
UnknownA new sexannulate species of Orobdella (Hirudinida, Arhynchobdellida, Orobdellidae) from Yakushima Island, Japan.
Not available
S-EPMC3332023 | biostudies-literature
UnknownAdult T-cell leukemia cells are characterized by abnormalities of Helios expression that promote T cell growth.
Not available
S-EPMC7657222 | biostudies-literature
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