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ModelsYugi2014 - Insulin induced signalling (PFKL phosphorylation) - model 1
Yugi2014 - Insulin induced signalling (PFKL phosphorylation) - model 1 Insulin induces phosphorylation and activation of liver-type phosphofructokinase 1, which thereby controls a key reaction in glycolysis. This mechanism is revealed using the mathematical model. In this model, the PFKL ph...
2024-09-02 | BIOMD0000000540 | BioModels
ModelsYugi2014 - Insulin induced signalling (PFKL phosphorylation) - model 2
Yugi2014 - Insulin induced signalling (PFKL phosphorylation) - model 2 Insulin induces phosphorylation and activation of liver-type phosphofructokinase 1, which thereby controls a key reaction in glycolysis. This mechanism is revealed using the mathematical model. In this model, the PFKL ph...
2024-09-02 | BIOMD0000000541 | BioModels
ProteomicsInsulin response in mouse liver
Phosphoproteomics of mouse liver over a period of four hours after insulin administration. It is part of a larger project that contains multi-omic datasets.
ORGANISM(S): Mus musculus (Mouse) 
2021-08-25 | PXD022823 | Pride
Mouse Insulin Liver 
ProteomicsInsulin response in mouse liver
Proteomics of mouse liver over a period of four hours after insulin administration. It is part of a larger project that contains multi-omic datasets.
ORGANISM(S): Mus musculus (Mouse) 
2021-08-25 | PXD022728 | Pride
Mouse Insulin Liver 
TranscriptomicsGenome-wide gene expression profiling revealed a critical role for GATA3 in the maintenance of the Th2 cell identity
Functionally polarized CD4+ T helper (Th) cells such as Th1, Th2 and Th17 cells are central to the regulation of acquired immunity. However, the molecular mechanisms governing the maintenance of the polarized functions of Th cells remain unclear. GATA3, a master regulator of Th2 cell differentiation...
ORGANISM(S): Mus musculus 
2013-04-19 | E-GEOD-46185 | biostudies-arrayexpress
ProteomicsProteome analysis of mouse liver and skeletal muscle
The liver and skeletal muscle were collected from 10-week-old wild-type and ob/ob mice fasted for 16 hours. Tissues were frozen immediately and lysed with 0.5 mL of a solution containing 50 mM Tris-HCl pH8.8, 2%SDS, and 7 M urea, and then subjected to ultrasonic treatment with a Bioruptor (Digaenode...
ORGANISM(S): Mus Musculus (mouse) 
2021-03-03 | PXD020656 | JPOST Repository
GenomicsThe polycomb protein Ezh2 regulates differentiation and plasticity of CD4 T helper type-1 and type-2 cells [ChIP-seq]
Following antigen encounter by CD4 T cells, polarizing cytokines induce the expression of master regulators that control differentiation. Inactivation of the histone methyltransferase Ezh2 was found to specifically enhance T-helper (Th)1 and Th2 cell differentiation and plasticity. Ezh2 directly bo...
ORGANISM(S): Mus musculus 
2013-09-24 | E-GEOD-51079 | biostudies-arrayexpress
TranscriptomicsThe polycomb protein Ezh2 regulates differentiation and plasticity of CD4 T helper type-1 and type-2 cells.
Following antigen encounter by CD4 T cells, polarizing cytokines induce the expression of master regulators that control differentiation. Inactivation of the histone methyltransferase Ezh2 was found to specifically enhance T-helper (Th)1 and Th2 cell differentiation and plasticity. Ezh2 directly bo...
ORGANISM(S): Mus musculus 
2013-09-11 | E-GEOD-50729 | biostudies-arrayexpress
ProteomicsPhosphoprotoemics analysis of FAO cells stimulated with insulin
FAO cells, rat hepatoma cells, were stimulated with 1 nM insulin and collected at seven time points for ~60 minutes. Ion metal affinity chromatography (IMAC) was performed to enrich the phosphopeptides. As we used two sets of 4-plex iTRAQ to quantify the peptides from seven samples, we set the inter...
ORGANISM(S): Rattus Rattus (black Rat) 
2018-11-30 | PXD005900 | JPOST Repository
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