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GenomicsNaloxone influences NSCs proliferation and differentiation
Naloxone influences NSCs proliferation and differentiation
PRJNA416497 | ENA
GenomicsEffects of naloxone on NSC proliferation and differentiation
Effects of naloxone on NSC proliferation and differentiation
PRJNA416070 | ENA
GenomicsDNA methylation maps of mouse NSCs treated with naloxone
DNA methylation maps of mouse NSCs treated with naloxone
PRJNA420451 | ENA
ProteomicsNaloxone induced alterations in liver proteome and cholesterol level in ApoE-/- mice.
The endogenous opioid system plays a pivotal role in numerous physiological processes and is implicated in a range of diseases, including atherosclerosis, a condition contributing to nearly 50% of deaths in Western societies. This study investigates the effects of opioid receptor blockade using nalo...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-09 | PXD063243 | Pride
Opioid receptors  cholesterol  atherosclerotic plaque  liver steatosis 
TranscriptomicsNaloxone influences NSCs proliferation and differentiation
Naloxone is an opioid-receptor antagonist used to reverse the effects of opioid.In our study, we treated NSCs (neural stem cells) with naloxone and damgo (a selective μopioid receptor agonist), and examined their effects on NSCs proliferation and differentiation.Naloxone was found to promote NSCs pr...
ORGANISM(S): Mus musculus 
2020-03-04 | GSE106376 | GEO
Methylation profilingDNA methylation maps of mouse NSCs treated with naloxone
In our study,we examined the effects of naloxone (an opioid receptor antagonist) on NSCs (neural stem cells) proliferation and differenntiation. Briefly, we treated NSCs with naloxone in the proliferation and differentiation system. Naloxone was shown to acclerate NSCs proliferation and increase neu...
ORGANISM(S): Mus musculus 
2020-03-04 | GSE107525 | GEO
TranscriptomicsEffects of naloxone on NSC proliferation and differentiation
Naloxone is an opioid-receptor antagonist used to reverse the effects of opioid.In our study, we treated NSCs (neural stem cells) with naloxone and damgo (a selective μopioid receptor agonist), and examined their effects on NSCs proliferation and differentiation.Naloxone was found to promote NSCs pr...
ORGANISM(S): Mus musculus 
2020-10-27 | GSE106263 | GEO
TranscriptomicsAnalgesia of naloxone and morphine in wild-type and NY1DD sickle cell mice using BMAP cDNA microarrays
Sickle cell disease is the most common genetic disorder in African-Americans. The opioid analgesic, morphine, has long been the treatment for the severe pain associated with this disease. Here we reveal that the opioid antagonist, naloxone, possesses potent analgesic activity in two strains of sickl...
ORGANISM(S): Mus musculus 
2007-12-20 | GSE6479 | GEO
UnknownGuidance on take-home naloxone distribution and use by community overdose responders in Canada.
Not available
S-EPMC10462409 | biostudies-literature
UnknownEffectiveness of Scotland's National Naloxone Programme for reducing opioid-related deaths: a before (2006-10) versus after (2011-13) comparison.
Not available
S-EPMC4982071 | biostudies-literature
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