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UnknownOn the Strong Binding Affinity of Gold-Graphene Heterostructures with Heavy Metal Ions in Water: A Theoretical and Experimental Investigation.
Minimum energy configurations in 2D material-based heterostructures can enable interactions with external chemical species that are not observable for their monolithic counterparts. Density functional theory (DFT) calculations reveal that the binding energy of divalent toxic metal ions of Cd, Pb, an...
S-EPMC11448048 | biostudies-literature
TranscriptomicsA Model System for Studying the Transcriptomic and Physiological Changes Associated with Mammalian Host-Adaptation by Leptospira interrogans Serovar Copenhageni
Leptospirosis, an emerging zoonotic disease with worldwide distribution, is caused by spirochetes belonging to the genus Leptospira. More than 500,000 cases of severe leptospirosis are reported annually, with .10% of these being fatal. Leptospires can survive for weeks in suitably moist conditions b...
ORGANISM(S): Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 
2014-03-20 | E-GEOD-53818 | biostudies-arrayexpress
TranscriptomicsChIP-chip of wild_type and K14MycER in Mouse genome wide proximal promoter regions
Identification of c-Myc and H3K4me3 enriched genomic regions in normal or c-Myc overexpressed mouse epidermis
ORGANISM(S): Mus musculus 
2011-10-26 | E-MTAB-555 | biostudies-arrayexpress
TranscriptomicsRNAseq of epidermis reconstructed from TSG-6-/- and TSG-6+/+ immortalized N/TERT keratinocytes and stimulated or not with interleukins 4 and 13 for 48h
TNFα-stimulated gene 6 (TSG-6) is an anti-inflammatory protein. In human epidermis, TSG-6 is secreted in extracellular matrix where it interacts with hyaluronan (HA). However, their functions are not well understood. In this study, immortalized N/TERT keratinocytes were edited by CRISPR/Cas9, used t...
ORGANISM(S): Homo sapiens 
2021-12-30 | E-MTAB-10095 | biostudies-arrayexpress
TranscriptomicsDecoding the black box of cellulase formation in Hypocrea jecorina by RNA-Seq analysis
Hypocrea jecorina (anamorph Trichoderma reesei) is one of the most well studied fungi used in biotechnology industry. This fungus is today a paradigm for the comercial scale production of different plant cell wall degrading enzymes, mainly cellulases and hemicellulases. The objective of this study w...
ORGANISM(S): Trichoderma reesei 
2014-04-01 | E-GEOD-53629 | biostudies-arrayexpress
UnknownSARS-CoV-2 antibody dynamics in blood donors and COVID-19 epidemiology in eight Brazilian state capitals: A serial cross-sectional study.

Background

The COVID-19 situation in Brazil is complex due to large differences in the shape and size of regional epidemics. Understanding these patterns is crucial to understand future outbreaks of SARS-CoV-2 or other respiratory pathogens in the country.

Methods

We tested 97,950 blo...
S-EPMC9545556 | biostudies-literature
UnknownFunctional plasticity shapes neutrophil response to Leishmania major infection in susceptible and resistant strains of mice.
Neutrophils rapidly infiltrate sites of infection and possess several microbicidal strategies, such as neutrophil extracellular traps release and phagocytosis. Enhanced neutrophil infiltration is associated with higher susceptibility to Leishmania infection, but neutrophil effector response contribu...
S-EPMC11488723 | biostudies-literature
UnknownEffect of Bacille Calmette-Guerin vaccination on immune responses to SARS-CoV-2 and COVID-19 vaccination.

Objectives

Bacille Calmette-Guérin (BCG) vaccination has off-target effects on disease risk for unrelated infections and immune responses to vaccines. This study aimed to determine the immunomodulatory effects of BCG vaccination on immune responses to vaccines against SARS-CoV-2.

Methods<...

S-EPMC11761716 | biostudies-literature
TranscriptomicsRegulation of Gene Expression and Parent-of-Origin Effects in Maize Hybrids
Heterosis (hybrid vigor) refers to the superior performance of hybrid progeny relative to their parents. Although widely exploited in agriculture, the mechanisms responsible for heterosis are not well understood. As a monoecious organism, a given maize plant can be used as both male and female par...
ORGANISM(S): Zea mays 
2009-11-20 | E-GEOD-16136 | biostudies-arrayexpress
UnknownOff-target effects of bacillus Calmette-Guerin vaccination on immune responses to SARS-CoV-2: implications for protection against severe COVID-19.

Background and objectives

Because of its beneficial off-target effects against non-mycobacterial infectious diseases, bacillus Calmette-Guérin (BCG) vaccination might be an accessible early intervention to boost protection against novel pathogens. Multiple epidemiological studies and randomi...
S-EPMC9028103 | biostudies-literature
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