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TranscriptomicsPU.1 and C/EBPalpha synergistically program distinct response to NF-kappaB activation through establishing monocyte specific enhancers (expression data)
Unraveling the complexity of transcriptional programs coded by different cell types has been one of the central goals of cell biology. Using genome-wide location analysis, we examined how two different cell types generate different responses to the NF-kappaB signaling pathway. We showed that, after ...
ORGANISM(S): Homo sapiens 
2011-03-15 | E-GEOD-26868 | biostudies-arrayexpress
TranscriptomicsHigh-throughput sequencing of endogenous small RNAs from rat vascular smooth muscle cells with and without Angiotensin II stimulation
Angiotensin II (Ang II)-mediated vascular smooth muscle cells (VSMC) dysfunction plays a critical role in cardiovascular diseases. However, the role of microRNAs (miRNAs) in this process is unclear. We used small RNA deep sequencing to profile Ang II-regulated miRNAs in rat VSMC and evaluated their ...
ORGANISM(S): Rattus norvegicus 
2012-03-23 | E-GEOD-35664 | biostudies-arrayexpress
GenomicsTE-associated chromatin variation in mice livers
Chromatin accessibility is a hallmark of active regulatory function in the genome and variation of chromatin accessibility across individuals has been shown to contribute to complex traits and disease susceptibility. However, the mechanisms responsible for chromatin variation among different individ...
ORGANISM(S): Mus musculus 
2016-07-14 | E-GEOD-75770 | biostudies-arrayexpress
UnknownSmartphone-based blood pressure monitoring via the oscillometric finger-pressing method.
Not available
S-EPMC6039119 | biostudies-literature
TranscriptomicsDiet-induced chromatin remodeling in mice livers
The tissue-specific packaging of the genome into the nucleus through chromatin is fundamentally involved in gene regulation, and aberrant modifications to chromatin are a hallmark of many diseases. We show here that a high fat (HF) diet leads to substantial chromatin remodeling in the livers of C57B...
ORGANISM(S): Mus musculus 
2014-07-17 | E-GEOD-55581 | biostudies-arrayexpress
TranscriptomicsChip-chip from THP1 cells with H3K56Ac
THP1 cells were ChIPed with H3K56Ac Comparison of selected chromatin marks in THP1 cells
ORGANISM(S): Homo sapiens 
2013-02-15 | E-GEOD-43868 | biostudies-arrayexpress
TranscriptomicsChip-chip from THP1 cells with H3K4me3, H3K9me2 , H3K27me3, JARIDIA, LSD1, JHDM1A, JHDM2A, JHDM3A, SIN3A, SNF2H, BRG1
THP1 cells were ChIPed with indicated antibodies. Comparison of selected chromatin marks in THP1 cells
ORGANISM(S): Homo sapiens 
2013-02-15 | E-GEOD-43869 | biostudies-arrayexpress
TranscriptomicsChip-chip from THP1 cells with Pol II, Pol II Ser5-P, H3K9Ac and from primary monocytes with H3K4Me3
THP1 cells were ChIPed with indicated antibodies. Comparison of selected chromatin marks in THP1 cells and monocytes
ORGANISM(S): Homo sapiens 
2013-02-15 | E-GEOD-43870 | biostudies-arrayexpress
GenomicsPalmitic acid induced lncRNA PARAIL regulates inflammation via interaction with RNA-binding protein HuR in monocytes and macrophages
Palmitic acid induced lncRNA PARAIL regulates inflammation via interaction with RNA-binding protein HuR in monocytes and macrophages
PRJNA884278 | ENA
UnknownRepurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results.
Not available
S-EPMC7727327 | biostudies-literature
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