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TranscriptomicsM. tuberculosis (Mtb) Produces Nitrite in Human Macrophages in Physiologic Oxygen to Impact Mycobacterial ATP Consumption and Gene Expression
We sequenced mRNA from Mtb that had been treated with 5 mM nitrate or was untreated in standard 7H9/ADNaCl medium. This generated the first analysis of gene expression following mycobacterial nitrate respiration. Examination of mRNA levels in Mtb following nitrate respiration, which results in the p...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2013-10-21 | E-GEOD-51037 | biostudies-arrayexpress
TranscriptomicsA Novel Gene Regulates Vesiculogenesis and Immunomodulation in Mycobacterium tuberculosis
After co-evolving with humans, its only major host, Mycobacterium tuberculosis (Mtb) restrains immune responses well enough to escape eradication, yet elicits enough immunopathology to ensure its transmission. Here, we provide evidence that this balance is regulated in part by a previously uncharact...
ORGANISM(S): Mus musculus 
2013-12-03 | E-GEOD-50050 | biostudies-arrayexpress
UnknownKaposi's sarcoma-associated herpesvirus LANA-1 interacts with the short variant of BRD4 and releases cells from a BRD4- and BRD2/RING3-induced G1 cell cycle arrest.
Not available
S-EPMC1641788 | biostudies-literature
TranscriptomicsImpact of mutations in rv2887, putative transcriptional repressor, on gene expression in Mycobacterium tuberculosis.
This study was aimed towards understanding the consequences of mutating rv2887, a putative transcriptional repressor, on gene expression in Mycobacterium tuberculosis. Since clones carrying mutations in this gene were found to be highly resistant to a potent mycobactericidal compound, 14, we also te...
ORGANISM(S): Mycobacterium tuberculosis 
2016-07-01 | E-GEOD-77556 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse skeletal muscle-specific, conditional transgenic mouse expressing a constitutively-active form of Akt1
In contrast to the well-established role of oxidative muscle fibers in regulating fatty acid oxidation and whole body metabolism, little is known that about the function of fast/glycolytic muscle fibers in these processes. Here, we generated a skeletal muscle-specific, conditional transgenic mouse e...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9484 | biostudies-arrayexpress
UnknownEmbroidered Silk Fibroin Scaffolds for ACL Tissue Engineering.
Not available
S-EPMC12786107 | biostudies-literature
TranscriptomicsTranscription profiling of human skeletal muscle from Hiv-Infected Men experiencing weight loss treated with testosterone
Context: Although androgen treatment increases muscle mass in HIV-infected men, the underlying mechanisms are poorly understood. Analysis of genome-wide microarray data obtained from skeletal muscle biopsies can be used to profile androgen-regulated pathways. Objective: To identify genes and pathway...
ORGANISM(S): Homo sapiens 
2009-04-10 | E-GEOD-5106 | biostudies-arrayexpress
UnknownLandscape Simplification Modifies Trap-Nesting Bee and Wasp Communities in the Subtropics.
Not available
S-EPMC7760584 | biostudies-literature
UnknownLong-term inhaled treprostinil for pulmonary hypertension due to interstitial lung disease: INCREASE open-label extension study.
Not available
S-EPMC10307984 | biostudies-literature
TranscriptomicsCharacterization of regulatory mutants in Mycobacterium tuberculosis
In this study, we report the identification and characterization of several regulators in Mycobacterium tuberculosis. WT and mutant Mtb cells were grown in Sauton minimal media to early stationary phase (OD580 = 2 and 4)
ORGANISM(S): Mycobacterium tuberculosis 
2010-09-29 | E-GEOD-23947 | biostudies-arrayexpress
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