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TranscriptomicsIdentification and Comparative Analyses of Myocardial miRNAs Involved in Fetal Response to Maternal Obesity
Maternal obesity programs the offspring to cardiovascular disease, insulin resistance, and obesity. We sequenced and profiled the cardiac miRNAs that were dysregulated in the hearts of baboon fetuses born to a high fat / high fructose diet fed mothers compared to a regular diet fed mothers. Fetal he...
ORGANISM(S): Papio hamadryas 
2013-02-01 | E-GEOD-43323 | biostudies-arrayexpress
MetabolomicsSexual dimorphism in the fetal cardiac response to maternal nutrient restriction
Poor maternal nutrition causes intrauterine growth restriction (IUGR); however, its effects on fetal cardiac development are unclear. We have developed a baboon model of moderate maternal undernutrition, leading to IUGR. We hypothesized that the IUGR affects fetal cardiac structure and metabolism. S...
2018-04-30 | MTBLS426 | MetaboLights
TranscriptomicsExpression of the placental transcriptome in fetal growth restriction in the Baboon is Dependent on Fetal Sex
Fetal growth restriction (FGR) develops when fetal nutrient availability is compromised and increases the risk for perinatal complications and predisposes for offspring obesity, diabetes and cardiovascular disease later in life. Emerging evidence implicates changes in placental function in altered f...
ORGANISM(S): Papio hamadryas 
2013-12-06 | E-GEOD-40878 | biostudies-arrayexpress
TranscriptomicsIdentification and Comparative Analyses of Myocardial miRNAs Involved in Fetal Response to Maternal Undernutrition
Poor maternal nutrition during pregnancy causes intrauterine growth retardation, which, in turn, is associated with increased risk of cardiovascular and metabolic diseases in later life Fetal hearts were collected from baboon fetuses born to regularly fed and undernurished mothers. Total RNA was i...
ORGANISM(S): Papio hamadryas 
2015-11-02 | E-GEOD-69609 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Baboon (Papio anubis) cerebral cortex from neonates consuming long-chain polyunsaturated fatty acid formulas
Docosahexaenoic acid (DHA, 22:6n-3) and arachidonic acid (ARA, 20:4n-6) are the major long chain polyunsaturated fatty acids (LCPUFA) of the central nervous system. We examined the alterations in transcriptional profiles in neonate baboon cerebral cortex brain tissue using high-density Affymetrix ol...
ORGANISM(S): Papio anubis 
2007-10-25 | E-GEOD-6519 | biostudies-arrayexpress
TranscriptomicsDepot-dependent effects of maternal nutrient restriction on baboon fetal preadipocyte global gene profiles
Suboptimal intrauterine nutrition predisposes the fetus to central obesity and metabolic syndrome in adult life, suggesting nutritional programming of the fat distribution. However, the underlying mechanisms are not elucidated. We hypothesized that prenatal nutritional deprivation leads to stimulat...
ORGANISM(S): Papio 
2011-12-16 | E-GEOD-34464 | biostudies-arrayexpress
UnknownUniversal DNA methylation age across mammalian tissues.
Not available
S-EPMC10501909 | biostudies-literature
UnknownDNA methylation networks underlying mammalian traits.
Not available
S-EPMC11180965 | biostudies-literature
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