Native chemical ligation

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Testing the effect of histone native chemical ligation on protein binding to di-nucleosomes

Here we examined whether histones H3 and H4 produced using native chemical ligation reaction affect protein binding to di-nucleosomes. To test this we performed a set of affinity purification pull-downs using di-nucleosomes containing the following histones H3 and H4: 1. unmodified ligated histone ...

ORGANISM(S): Homo sapiens (Human)

2023-12-12 | PXD042390 | Pride