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MetabolomicsLinking soil biology and chemistry in biological soil crust using isolate exometabolomics
Metagenomic sequencing provides a window into microbial community structure and metabolic potential; however, linking these data to exogenous metabolites that microorganisms process and produce (the exometabolome) remains challenging. Previously, we observed strong exometabolite niche partitioning a...
2018-07-31 | MTBLS492 | MetaboLights
MetabolomicsUntargeted LC–HRMS Intracellular Metabolomic Fingerprinting Reveals Isolate-Specific Chemical Biodiversity in Sugarcane-Derived Endophytic Bacteria

Endophytic bacteria are underexplored reservoirs of molecular diversity. We compared the intracellular metabolomic fingerprints of three endophytic bacterial isolates from sugarcane (Saccharum officinarum), assigned to Streptomyces sp., Pantoea sp., and Paracoccus sp. Extracts from three independ...

2026-10-08 | MTBLS15815 | MetaboLights
TranscriptomicsThe transcriptional consequences of mutation and natural selection in Caenorhabditis elegans
This set of arrays contains all microarray experiments done involving comparisons among C. elegans natural isolates and mutation-accumulation lines. Abstract: The evolutionary importance of gene-expression divergence is unclear: some studies suggest that it is an important mechanism for evolution by...
ORGANISM(S): Caenorhabditis elegans 
2006-01-31 | E-GEOD-4123 | biostudies-arrayexpress
GenomicsSaccharomyces cerevisiae strain:Natural isolate | isolate:YI38
Natural Saccharomyces cerevisiae isolate QTL analysis
PRJNA517782 | ENA
ProteomicsS. cerevisiae natural isolate proteomics
Natural S. cerevisiae isolates were evaluated for tolerance to a complex mixture of lignocellulosic inhibitors. Two isolates, with intermediate and superior tolerance characteristics, were investigated to determine the proteomic changes required for tolerance to lignocellulosic inhibitors.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-11-02 | PXD010868 | Pride
Natural isolate Saccharomyces Lignocellulosic inhibitors 
TranscriptomicsNovel viruses naturally infecting Caenorhabditis nematodes trigger a small RNA response
C. elegans has served as a laboratory model organism due to its ease of manipulation and the availability of both forward and reverse genetics. In recent years, efforts to study host-pathogen interactions in C. elegans have increased. For example, analysis of infections by bacteria such as Pseudomon...
ORGANISM(S): Caenorhabditis elegans 
2011-01-01 | E-GEOD-21736 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of different developmental stages of a novel natural isolate of the model organism Ashbya gossypii
This is a transcriptome analysis of a novel A. gossypii natural isolate at different developmental stages. Individual transcription profiles were developed from spores to bipolar germlings (time frame 9 h) and to very fast growing hyphae at the border of colony growing with maximal speed on plates (...
ORGANISM(S): Ashbya gossypii 
2011-01-31 | E-MEXP-1955 | biostudies-arrayexpress
TranscriptomicsMutation in Transcription Factor Upc2p Causes Upregulation of Ergosterol Biosynthesis Genes and Fluconazole Resistance
In the pathogenic yeast Candida albicans, the zinc cluster transcription factor Upc2p has been shown to regulate expression of ERG11 and other genes involved in ergosterol biosynthesis upon exposure to azole antifungals. ERG11 encodes lanosterol demethylase, the target enzyme of this antifungal cla...
ORGANISM(S): Candida albicans 
2008-11-04 | E-GEOD-11320 | biostudies-arrayexpress
GenomicsHuman Calu-3 cell transcriptome response to wild-type pandemic H1N1 (A/California/04/2009), natural isolate
The purpose is to obtain samples for mRNA, miRNA, proteomics, lipidomics, metabolomics, and histopathology analysis in human Calu-3 cells infected with wild-type pandemic H1N1 (A/California/04/2009), natural isolate.
ORGANISM(S): Homo sapiens 
2016-05-07 | GSE80698 | GEO
TranscriptomicsHuman Calu-3 cell transcriptome response to wild-type pandemic H1N1 (A/California/04/2009), natural isolate [mRNA]
The purpose is to obtain samples for mRNA, miRNA, proteomics, lipidomics, metabolomics, and histopathology analysis in human Calu-3 cells infected with wild-type pandemic H1N1 (A/California/04/2009), natural isolate.
ORGANISM(S): Homo sapiens 
2016-05-26 | GSE80697 | GEO
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