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ProteomicsPhosphorylated Tau Interactome in the Human Alzheimers Disease Brain
Accumulation of phosphorylated tau is a key pathological feature of Alzheimers disease. Phosphorylated tau accumulation causes synaptic impairment, neuronal dysfunction and formation of neurofibrillary tangles. The pathological actions of phosphorylated tau are mediated by surrounding neuronal prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-04-17 | MSV000085305 | MassIVE
ProteomicsIn-depth Mass Spectrometry Analysis Reveals the Plasma Proteomic and N-glycoproteomic Impact of an Amish Enriched Cardioprotective Variant in B4GALT1
Proteome and N-glycoproteome in human plasma were analyzed and compared between B4GALT1 WT and N352S genotypes. The results showed that N352S significantly decreased galactosylation for a wide range of proteins, especially apoB and fibrinogen, which may be associated with the decreased LDL-c level o...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-12-29 | MSV000090976 | MassIVE
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