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ProteomicsIntegrin alpha1 beta1 promotes interstitial fibrosis and cyst growth in a mouse model of polycystic kidney disease
Background: Cystogenesis and interstitial fibrosis are contributing factors to kidney failure in individuals with autosomal dominant polycystic kidney disease (ADPKD). The molecular and cellular mechanisms involved in cyst growth and fibrosis are complex and new therapies are urgently needed to impr...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-07 | PXD072214 | Pride
Ecm Cyst Kidney Integrin 
TranscriptomicsNucleotide-resolution, genome-wide transcriptome maps of Propionibacterium acnes (cultured with and without potassium downshift)
This data contained within this entry was produced as part of a study that included differential RNA-sequencing and microarray analysis. The results of the latter two have also been deposited in GEO Duplicate cultures of Propionibacterium acnes strain KPA171202 were grown exponentially in Holland S...
ORGANISM(S): Propionibacterium acnes KPA171202 
2013-05-15 | E-GEOD-46883 | biostudies-arrayexpress
MetabolomicsSex-specific effects of CD248 on metabolism and the adipose tissue lipidome

Cd248 has recently been associated with adipose tissue physiology, demonstrated by reduced weight gain in high fat diet-fed mice with genetic deletion of Cd248 relative to controls. Here we set out to determine the metabolic consequences of loss of Cd248. Strikingly, we find these to be sex speci...

2023-01-05 | MTBLS6615 | MetaboLights
UnknownHand and torso pre-cooling does not enhance subsequent high-intensity cycling or cognitive performance in heat.
Not available
S-EPMC7518759 | biostudies-literature
UnknownSociodemographic Features, Health Care Costs, and Treatment Implications of Genomic Classifier Testing for Localized Prostate Cancer in the United States.
Not available
S-EPMC12370275 | biostudies-literature
UnknownPatient Factors Linked with Return Acute Healthcare Use in Older Adults by Discharge Disposition.
Not available
S-EPMC8352071 | biostudies-literature
UnknownProject ACHIEVE - using implementation research to guide the evaluation of transitional care effectiveness.
Not available
S-EPMC4759940 | biostudies-literature
UnknownRapid and contrasting effects of rosiglitazone on transient receptor potential TRPM3 and TRPC5 channels.
Not available
S-EPMC3102547 | biostudies-literature
TranscriptomicsThe anti-proliferative effects of progestins in T47D breast cancer cells are tempered by progestin-induction of the ETS transcription factor Elf5.
Prolactin and progesterone act together to regulate mammary alveolar development, and both hormones have been implicated in breast cancer initiation and progression. Here we show that Elf5, a prolactin-induced ETS transcription factor that specifies the mammary secretory cell lineage, is also induce...
ORGANISM(S): Homo sapiens 
2010-07-08 | E-GEOD-22363 | biostudies-arrayexpress
UnknownPeptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic β-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries.
Not available
S-EPMC8717237 | biostudies-literature
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