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MetabolomicsMetabolomic Profiling of Renal Cyst Fluid in Advanced ADPKD: Insights from Dialysis and Transplantation Cohorts

Background: Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disorder characterized by progressive renal cyst formation, often leading to end-stage kidney disease (ESKD). While urinary metabolomics in ADPKD has been extensively studied, the composition of renal cyst fluid, par...

2025-07-07 | MTBLS12372 | MetaboLights
MetabolomicsGlobal Metabolomic Profiling of Mice Brains following Experimental Infection with the Cyst-Forming Toxoplasma gondii
The interplay between the Apicomplexan parasite Toxoplasma gondii and its host has been largely studied. However, molecular changes at the metabolic level in the host central nervous system and pathogenesis-associated metabolites during brain infection are largely unexplored. We used a global metabo...
2017-01-27 | MTBLS217 | MetaboLights
MetabolomicsMetabolic profiling of cyst fluid from patients with Intraductal Pancreatic Mucinous Neoplasm
Not available
ORGANISM(S): Homo sapiens 
ST000713 | MetabolomicsWorkbench
ProteomicsComparative Proteomic Study of Entamoeba histolytica Trophozoites, Cysts, and Cyst-Like Structures
Proteomic comparison between trophozoites, cysts and cyst-like structures of Entamoeba histolytica
ORGANISM(S): Entamoeba Histolytica (ncbitaxon:5759) 
2016-04-21 | MSV000079674 | MassIVE
MetabolomicsMetabolic profiling of cyst fluid from patients with Intraductal Pancreatic Mucinous Neoplasm (part II)
Not available
ORGANISM(S): Homo sapiens 
ST000823 | MetabolomicsWorkbench
ProteomicsQuantitative Proteomic Profiling for Predicting Grade of Dysplasia in Intraductal Papillary Mucinous Neoplasm using Pancreatic Cyst Fluid
The increased number of pancreatic cyst lesions (PCLs) have been detected through the development of abdominal imaging techniques, such as computed tomography (CT), magnetic resonance imaging (MRI), and endoscopic ultrasound (EUS). However, accurate classification of cystic lesions is difficult beca...
ORGANISM(S): Homo sapiens (Human) 
2020-09-06 | PXD016127 | Pride
Mucinous cystic neoplasm (mcn) Pancreatic cyst fluid Biomarkers Intraductal papillary mucinous neoplasm (ipmn) Serous cystic neoplasm (scn) Lc-ms/ms 
ProteomicsQuantitative Proteomic Analysis of Pancreatic Cyst Fluid Proteins Associated with Malignancy in Intraductal Papillary Mucinous Neoplasms
Intraductal papillary mucinous neoplasm (IPMN) is a benign tumor that grows within the pancreatic ducts characterized by the production of thick mucinous fluid by surrounding tumor cells. IPMN is the most important precursor lesion for pancreatic cancer that is the fourth most common cause of cancer...
ORGANISM(S): Homo sapiens (Human) 
2018-05-01 | PXD008302 | Pride
Ipmn dysplasia Mucinous cystic neoplasm (mcn) Biomarker candidates Pancreatic cyst fluid Intraductal papillary mucinous neoplasm (ipmn) Lc-ms/ms 
ProteomicsComprehensive Proteomic Characterization of Human Pancreatic Cyst Fluid from Intraductal Papillary Mucinous Neoplasm by LC-MS/MS
Intraductal papillary mucinous neoplasm (IPMN) is a duct-dilating precancerous lesion that grows in pancreatic ducts and is accompanied by the production of mucinous fluid. In recent years, its cystic fluid has been used molecularly for the differential diagnosis of other cystic tumors and malignanc...
ORGANISM(S): Homo sapiens (Human) 
2017-08-22 | PXD005671 | Pride
Pancreatic cyst Protein mutation Intraductal papillary mucinous neoplasm 
ProteomicsIdentification and characterization of Acanthamoeba cyst wall proteins
Acanthamoeba castellanii, cause of keratitis and blindness, is an emerging pathogen because of its association with contact lens use. The cyst wall contributes to pathogenesis as cysts are resistant to sterilizing reagents in lens solutions and to antibiotics applied to the eye. Here we used struct...
ORGANISM(S): Acanthamoeba castellanii str. Neff 
2019-05-21 | PXD011826 | Pride
Cyst wall proteins Acanthamoeba Lectins 
ProteomicsDetermination of pancreatic cyst fluids peptidome and proteome
Determination of pancreatic cyst fluids (PCF) peptidome and proteome in 5 distinct patient groups: malignant (CAs), intraductal papillary mucinous neoplasms (IPMNs), mucinous cystic neoplasms (MCNs), serous cystic neoplasms (SCNs), and pseudocysts (PCs). The PCF <5kDa fraction, referred as the degra...
ORGANISM(S): Homo sapiens (Human) 
2019-01-14 | PXD005248 | Pride
Human Pancreas Cyst fluids Degradome Proteome Lc-ms/ms 
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