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Identification and validation of the BACE1 cleavage site in NCAM2 and NCAM1
ORGANISM(S): Mus musculus (Mouse) 
2021-02-04 | PXD021330 | Pride
NCAM1+ subpopulation of adult human kidney epithelial cells (hKEpC) can be specifically activated in vitro to stem-like cells that de-differentiate and recapitulate embryogenesis. We used microarrays to detail the global programme of gene expression in the NCAM1+ sub-population in comparison to NCAM...
ORGANISM(S): Homo sapiens 
Membranous lupus nephritis is a frequent cause of nephrotic syndrome in patients with systemic lupus erythematosus. Unlike phospholipase A2 receptor or thrombospondin type 1 domain containing 7A-associated membranous nephropathy, where known antibodies can be detected within sera by indirect immun...
ORGANISM(S): Homo sapiens (Human) 
2020-10-19 | PXD021123 | Pride
We present a time-resolved chemical proteomic strategy to track the early-stage entry of ZIKV into host cells. ZIKV was labeled on its surface with a chemical probe, which carries a photocrosslinker to covalently link virus-interacting proteins in living cells on UV exposure at different time points...
ORGANISM(S): Macaca mulatta (Rhesus macaque) 
2020-09-11 | PXD020119 | Pride
The prion protein (PrP) evolved from the subbranch of ZIP metal ion transporters comprising ZIPs 5, 6 and 10, raising the prospect that the study of these ZIPs may reveal insights relevant for understanding PrP function. PrP and ZIP6 are required for the execution of a cellular program known as epi...
ORGANISM(S): Mus musculus (Mouse) 
2017-02-13 | PXD004685 | Pride
NCAM1+ subpopulation of fetal human kidneyl cells are nephron progenitors We used microarrays to detail the global programme of gene expression in the NCAM1+ sub-population in comparison to total culture.
ORGANISM(S): Homo sapiens 
Targeting NCAM1/FGFR1 signaling to alleviate sleep disturbance-induced neuroinflammation in the hypothalamus
Neural cell adhesion molecule 1 (NCAM1 CD56) promotes leukemogenesis and confers drug resistance in acute myeloid leukemia.
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