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The ncBAF complex regulates transcription in AML through H3K27ac sensing by BRD9 (CUT&Run)
The ncBAF complex regulates transcription in AML through H3K27ac sensing by BRD9 (ATAC-Seq)
The ncBAF complex regulates transcription in AML through H3K27ac sensing by BRD9 (TT-Seq)
The non-canonical BAF complex (ncBAF) subunit BRD9 is essential for acute myeloid leukemia (AML) cell viability but has an unclear role in leukemogenesis. Because BRD9 is required for ncBAF complex assembly through its DUF3512 domain, precise bromodomain inhibition is necessary to parse the role of ...
ORGANISM(S): Homo sapiens 
2023-10-20 | GSE241427 | GEO
The non-canonical BAF complex (ncBAF) subunit BRD9 is essential for acute myeloid leukemia (AML) cell viability but has an unclear role in leukemogenesis. Because BRD9 is required for ncBAF complex assembly through its DUF3512 domain, precise bromodomain inhibition is necessary to parse the role of ...
ORGANISM(S): Homo sapiens 
2023-10-20 | GSE241425 | GEO
The non-canonical BAF complex (ncBAF) subunit BRD9 is essential for acute myeloid leukemia (AML) cell viability but has an unclear role in leukemogenesis. Because BRD9 is required for ncBAF complex assembly through its DUF3512 domain, precise bromodomain inhibition is necessary to parse the role of ...
ORGANISM(S): Homo sapiens 
2023-10-20 | GSE241424 | GEO
Differential requirements for the BAF and ncBAF subfamilies of the mammalian SWI/SNF chromatin remodeling enzymes during skeletal muscle differentiation.
The ncBAF complex regulates transcription in AML through H3K27ac sensing by BRD9
Subunit proteins BAF250a and Brd9 are specific to mammalian SWI/SNF subfamilies BAF and ncBAF respectively. We have performed RNA-seq analysis for C2C12 myoblasts stably knocked down for each subunits using specific shRNA constructs. C2C12 cells stably transfected with non-targeting scrambled shRNA ...
ORGANISM(S): Mus musculus 
2023-07-10 | GSE196281 | GEO
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