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Juvenile hormone (JH) serves vital roles in insect reproduction, development, and many aspects of physiology. JH primarily acts at the gene-regulatory level through an intracellular receptor. The JH receptor (JHR) is a ligand-activated complex of transcription factors of the bHLH-PAS family, consist...
ORGANISM(S): Tribolium castaneum (Red flour beetle) 
2022-02-16 | PXD028599 | Pride
Juvenile hormone (JH) serves vital roles in insect reproduction, development, and many aspects of physiology. JH primarily acts at the gene-regulatory level through an intracellular receptor. The JH receptor (JHR) is a ligand-activated complex of transcription factors of the bHLH-PAS family, consist...
ORGANISM(S): Tribolium castaneum (Red flour beetle) 
2022-02-16 | PXD028394 | Pride
High ploidy large cytoplasmic megakaryocytes (LCM) are critical negative regulators of hematopoietic stem cells (HSC) and are responsible for platelet formation. Using a mouse knockout model with normal megakaryocyte numbers but essentially devoid of LCM (MK-LCM KO), we demonstrated a pronounced inc...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD040423 | Pride
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