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TranscriptomicsThe effect of ERG overexpression and ERG knockdown by shRNA in RWPE1 and VCAP cells, respectively
The goal of this project was to analyze the global gene expression profiles of RWPE1 and VCAP cells following transfection of GFP, GFP-ERG at 48 and 72hrs time points and stable ERG shRNA, scramble shRNA, respectively. RWPE1 cells were transfected with GFP or GFP-ERG. VCAP cells were transfected wit...
ORGANISM(S): Homo sapiens 
2010-08-25 | E-GEOD-16671 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human pediatric alveolar (aRMS) and embryonal (eRMS) rhabdomyosarcoma, plus primary pediatric Ewings sarcoma (EWS)
Affymetrx U95Av2 GeneChip hybridizations, RNA extracted from primary human pediatric alveolar (aRMS) and embryonal (eRMS) rhabdomyosarcoma, plus primary pediatric Ewing's sarcoma (EWS)
ORGANISM(S): Homo sapiens 
2007-09-29 | E-GEOD-967 | biostudies-arrayexpress
TranscriptomicsSerum-Mediated Responses in Normal and Transformed Oral Keratinocyte Lines
Serum-driven responses, many of which are related to wound healing, are potentially deregulated in cancer development and associated genomic alterations might have prognostic value. The current study assessed fetal bovine serum-induced transcriptomic changes for clinical relevance in head and neck s...
ORGANISM(S): Homo sapiens 
2014-01-01 | E-GEOD-39376 | biostudies-arrayexpress
TranscriptomicsHSF1 Is Required for Tumor Progression whereas HSF2 Suppresses Invasiveness of Prostate
Prostate cancer (PrCa) is one of the most common malignancies in Western countries. However, the pathways that promote invasion, especially in late-stage castration-resistant PrCa (CRPC), are poorly understood. Heat shock factors (HSFs) are transcriptional regulators essential for cell survival upon...
ORGANISM(S): Homo sapiens 
2013-12-23 | E-GEOD-48672 | biostudies-arrayexpress
TranscriptomicsTranscript profiling of normal oral keratinocytes and the tongue squamous cell carcinoma line LK0412
The current study analyzed a unique, serum-free medium derived tongue squamous cell carcinoma (TSCC) line termed LK0412 relative to the normal state to elucidate biomarkers at the protein and transcript level. A bioinformatics approach using Gene Ontology categories, gene networks and signature eval...
ORGANISM(S): Homo sapiens 
2014-01-31 | E-GEOD-21866 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of human breast cancer cells MCF7 and LCC2 treated with Tamoxifen; EPZ or DMSO
RNA-Seq of human breast cancer cells MCF7 and LCC2 treated with Tamoxifen; EPZ or DMSO
ORGANISM(S): Homo sapiens 
2019-10-11 | E-MTAB-6892 | biostudies-arrayexpress
TranscriptomicsComprehensive Characterization of 3D Models for Prostate Cancer Growth and Invasion in Laminin-rich Extracellular Matrix
Full title: Comprehensive Characterization of Three-Dimensional Models for Prostate Cancer Growth and Invasion in Laminin-rich Extracellular Matrix Prostate Cancer (PrCa) cells undergo acinar morphogenesis and spheroid formation in three-dimensional (3D) culture, supported by laminin-rich extracellu...
ORGANISM(S): Homo sapiens 
2010-12-06 | E-GEOD-19426 | biostudies-arrayexpress
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